Sonochemical synthesis, structure and magnetic properties of air-stable Fe3O4/Au nanoparticles

Wu, Wei; He, Quanguo; Chen, Hong; Tang, Jianxin; Nie, Libo

doi:10.1088/0957-4484/18/14/145609

Cited by 152 publications

(88 citation statements)

References 35 publications

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“…Meanwhile, fructose assay demonstrated the potential of the NPs in detection of small molecules as well as the separation of bacteria. Wu et al [256] used (3-aminopropyl)triethoxysilane (APTES)-coated Fe 3 O 4 NPs as seeds to prepare the core/shell NPs via a sonochemical route. APTES-coated SPIONs were prepared by mixing of APTES with Fe 3 O 4 /ethanol suspension under vigorous stirring.…”

Section: Goldmentioning

confidence: 99%

Recent advances in surface engineering of superparamagnetic iron oxide nanoparticles for biomedical applications

Mahmoudi

Simchi

Imani

2010

JICS

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Superparamagnetic iron oxide nanoparticles (SPIONs) are promising materials for various biomedical applications including targeted drug delivery and imaging, hyperthermia, magneto-transfections, gene therapy, stem cell tracking, molecular/cellular tracking, magnetic separation technologies (e.g. rapid DNA sequencing), and detection of liver and lymph node metastases. The most recent applications for SPIONs for early detection of inflammatory, cancer, diabetes and atherosclerosis have also increased their popularity in academia. In order to increase the efficacy of SPIONs in the desired applications, especial surface coating/characteristics are required. The aim of this article is to review the surface properties of magnetic nanoparticles upon synthesis and the surface engineering by different coatings. The biological aspects, cytotoxicity, and health risks are addressed. Special emphasis is given to organic and inorganic-based coatings due to their determinant role in biocompatibility or toxicity of the final particles.

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Section: Goldmentioning

confidence: 99%

Recent advances in surface engineering of superparamagnetic iron oxide nanoparticles for biomedical applications

Mahmoudi

Simchi

Imani

2010

JICS

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“…This can be achieved by simply mixing two materials, such as metal alloys, or designing a core-shell structure. 88,89 For example, gold metal shells are of particular interest to many researchers due to bioinert properties of gold and plasmon resonance effects. 7,61 For example, Loo and researchers attached a cancer targeting antibody to gold nanoshells to provide targeted delivery to cancer cells.…”

Section: Types Of Core Particlesmentioning

confidence: 99%

Design of Multifunctional Nanomedical Systems

2009

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Multifunctional nanoparticles hold great promise for drug/gene delivery and simultaneous diagnostics and therapeutics ("theragnostics") including use of core materials that provide in vivo imaging and opportunities for externally modulated therapeutic interventions. Multilayered nanoparticles can act as nanomedical systems with on-board molecular programming done through the chemistry of highly specialized layers to accomplish complex and potentially decision-making tasks. The targeting process itself is a multi-step process consisting of initial cell recognition through cell surface receptors, cell entry through the membrane in a manner to prevent undesired alterations of the nanomedical system, re-targeting to the appropriate sub-region of the cell where the therapeutic package can be localized, and potentially control of that therapeutic process through feedback systems using molecular biosensors. This paper describes a bionanoengineering design process in which sophisticated nanomedical platform systems can be designed for diagnosis and treatment of disease. The feasibility of most of these subsystems has been demonstrated, but the full integration of these interacting sub-components remains a challenge for the field. Specific examples of sub-components developed for specific applications are described.

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“…Besides, the coating of the surface of magnetic NPs with a gold shell is essential in seeking to improve NPs biocompatibility and the chemical resistance of magnetic cores [9,10]. Based on this requirement, several methods, such as sonochemical treatment, galvanic replacement, reverse micelles, laser ablation and chemical reduction, among others, have been reported over the past decade for the attachment of gold to the surface of magnetite (Fe3O4) and maghemite (γ-Fe2O3) NPs [11][12][13][14][15][16][17][18][19][20][21]. For example, Lin et al [11] have synthesized core/shell Fe/Au NPs by a reverse-micelle approach.…”

Section: Introductionmentioning

confidence: 99%

Functionalization of Cobalt Ferrite Nanoparticles by a Vitamin C-Assisted Covering with Gold

Jagminas

Mažeika

Kondrotas

et al. 2014

Nanomaterials and Nanotechnology

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We report the design and methodology for functionalization of the surface of small Co-ferrite nanoparticles with a mean size of up to 5.0 nm through the attachment of vitamin C molecules initiating [AuCl4] -reduction and the subsequent deposition of gold. By this method, Co-ferrite-Au nanoparticles have been fabricated for the first time in a simple and controllable manner, consisting of the determination of the consumed ascorbic acid content. The sequential addition of vitamin C and HAuCl4 to the ferrofluid at low concentrations leads to the formation of a gold shell on the ferrite core. This approach avoids the additional stabilization of ferrite nanoparticles before gold deposition, and is of great importance in view of the preparation of biodegradable superparamagnetic particles for nanomedicine applications. The deposition of gold onto the ferrite surface was proved herein by UV-vis absorption and energydispersive X-ray (EDX) spectroscopy, inductively coupled plasma mass spectrometry analysis, atomic force microscopy (AFM), high resolution transmission electron microscopy (HRTEM) and Mössbauer spectroscopy.

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Sonochemical synthesis, structure and magnetic properties of air-stable Fe₃O₄/Au nanoparticles

Cited by 152 publications

References 35 publications

Recent advances in surface engineering of superparamagnetic iron oxide nanoparticles for biomedical applications

Recent advances in surface engineering of superparamagnetic iron oxide nanoparticles for biomedical applications

Design of Multifunctional Nanomedical Systems

Functionalization of Cobalt Ferrite Nanoparticles by a Vitamin C-Assisted Covering with Gold

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