2015
DOI: 10.7567/jjap.54.07hf16
|View full text |Cite
|
Sign up to set email alerts
|

Sonodynamically-induced cytotoxicity by rose bengal derivative and microbubbles in isolated sarcoma 180 cells

Abstract: It is known that the combination of ultrasound and sonodynamic sensitizer (SDS) is effective in noninvasive tumor treatment, referred to as sonodynamic therapy (SDT). Microbubbles have been used in ultrasound therapy as well. The purpose of this paper is to clarify the effect of microbubbles on SDT. Sarcoma 180 cells were suspended in air-saturated phosphate-buffered saline and exposed to ultrasound with the SDS rose bengal derivative (RBD) in standing wave mode in the presence and absence of microbubbles [son… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
1
1
1
1

Citation Types

0
13
0

Year Published

2016
2016
2023
2023

Publication Types

Select...
9

Relationship

2
7

Authors

Journals

citations
Cited by 12 publications
(13 citation statements)
references
References 36 publications
0
13
0
Order By: Relevance
“…These porphyrins include hematoporphyrin (Hp), photofrin, hematoporphyrin monomethyl ether (HMME), photoporphyrin IX (PpIX), ATX‐70 and some other porphyrin derivatives . In addition, erythrosine B (EB) and Rose Bengal (RB) as the typical Xanthenes were demonstrated to be effective in US‐triggered cytotoxicity to kill the cancer cells. Importantly, a number of anticancer drugs could act as the sonosensitizer for SDT, among which doxorubicin (DOX) was one of the most representative chemotherapeutic drug and sonosensitizer for cancer treatment .…”
Section: Traditional Organic Sonosensitizer Moleculesmentioning
confidence: 99%
“…These porphyrins include hematoporphyrin (Hp), photofrin, hematoporphyrin monomethyl ether (HMME), photoporphyrin IX (PpIX), ATX‐70 and some other porphyrin derivatives . In addition, erythrosine B (EB) and Rose Bengal (RB) as the typical Xanthenes were demonstrated to be effective in US‐triggered cytotoxicity to kill the cancer cells. Importantly, a number of anticancer drugs could act as the sonosensitizer for SDT, among which doxorubicin (DOX) was one of the most representative chemotherapeutic drug and sonosensitizer for cancer treatment .…”
Section: Traditional Organic Sonosensitizer Moleculesmentioning
confidence: 99%
“…In view that the amphiphilicity is favorable for accumulation of drugs in tumor, several amphiphilic RB derivatives have been synthesized. Sugita et al 47 combined carboxylation (RBD2) and alkylation (RBD3) to synthesize amphiphilic RB derivatives, which exhibit more efficient in vivo anticancer effects than RB under the ultrasound due to their enhanced accumulation in tumors 48 .…”
Section: Sonosensitizersmentioning
confidence: 99%
“…SDT can kill cancer cells by producing cytotoxic ROS through the combination of US with a sonosensitizer, while minimizing damage to the surrounding normal cells (Chen Y.-W. et al, 2016 ). Sonosensitizers include organic materials such as porphyrins (Hachimine et al, 2007 ; Yumita et al, 2010 ), erythrosine B (EB) (Yumita et al, 2002 ) and Rose Bengal (RB) (Sugita et al, 2015 ), as well as inorganic materials like titanium dioxide (TiO 2 ) (Harada et al, 2011 ) and silicon nanoparticles (Osminkina et al, 2015 ). Interesting, MSNs have been shown to have impressive SDT activity due to their high porosities, which allow the free diffusion of molecules to generate ROS.…”
Section: Chemotherapy and Sonodynamic Therapymentioning
confidence: 99%