Sp663lean Tissue Index Measured With Bioimpedance (Bia) and Strength and Physical Performance Tests Associated With Sarcopenia in a Hemodialysis Population

Abstract

nPCR) < 0.8 g/Kg/day and a Body Mass Index (BMI) <23 Kg/ m 2 . A p < 0.05 was considered significant. RESULTS: 1502 patients were included, with a median age of 73 years (IQR: 62-80) and a HD vintage of 48 months (IQR: 24-98). 57.2% were male and 36.4% were diabetics. The prevalence of PEW was 2.1% (n¼34). Patients with PEW had a higher median age (p<0.001) and HD vintage (p¼0.014); 68.8% were female (p¼0.003) and 18.8% were diabetics (p¼0.036). No statistical differences were found regarding the distribution of PEW across the country (NUTS II classification), neither in the educational level. A higher prevalence of PEW was seen in the afternoon shifts (p<0.001). Concerning the laboratory parameters, potassium (p<0.001), phosphorus (p<0.001), phosphorus-calcium product (p<0.001) and hemoglobin (p¼0.0013) were significantly lower in the PEW group. In regard to body composition, lean tissue mass and body cell mass were lower in these patients (p<0.001). Fat tissue mass was also lower in this group yet no statistically significant results were observed. Overhydration and Kt/V were not different between groups. We also found a greater prevalence of PEW in patients with venous catheter as vascular access (p¼0.030). CONCLUSIONS: The prevalence of PEW in the Portuguese population studied is relatively low (2.1%) when comparing to data reported in other countries. A poor nutritional status appeared to be associated with older age, HD vintage, gender, shift and vascular access. Patients diagnosed with PEW, through the combination of three parameters in the ISRNM recommendations, presented worse laboratory and body composition parameters.