Spaceflight breeding could improve the volatile constituents of Andrographis paniculata

Xia, Pengguo; Li, Qianqian; Liang, Zongsuo; Zhang, Xuemin; Ke, Yan

doi:10.1016/j.indcrop.2021.113967

Cited by 15 publications

(8 citation statements)

References 19 publications

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“…Among them, more than ten volatile compounds, mainly alcohols and aldehydes, including benzaldehyde, n-hexanol, etc., are all substances with large differences. Xia et al also had the same changes in their research on Andrographis paniculata for aerospace breeding [36]. This indicates that aerospace breeding will increase the levels of various VOCs in subsequent generations.…”

Section: Discussionmentioning

confidence: 80%

Analysis and Identification of Differences in Volatile Components of Various Alfalfa Seeds Based on GC-IMS

Zhao,

Zhu,

Yang

et al. 2024

Agronomy

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Volatile components are one key factor in sample identification, differential analysis, quality control and origin traceability. In order to identify and analyze the differences in volatile substances in different alfalfa seeds, this study used gas chromatography–ion mobility spectrometry (GC-IMS), combined with the Gallery Plot plug-in, and PCA, PLS-DA and other analysis methods. In this way, a comprehensive analysis of volatile components in 10 alfalfa seeds, including aerospace varieties, was conducted. A comparative analysis of the characteristics of different sample compounds using topographic maps and fingerprints led to isolation of 48 kinds of 54 volatile compounds. Among them, esters (9 types), olefins (8 types), ketones (8 types), alcohols (6 types) and aldehydes (6 types) were found to be the most abundant volatile compounds in alfalfa seeds. At the same time, PCA and PLS-DA analysis models showed that esters, ketones and alcohols were the main volatiles causing the differences among alfalfa seeds. Among them, the content of various substances in the ZT2 and ZT3 aerospace varieties were higher than that of other varieties, while the types and contents of volatiles in ZT1, ZM2 and GN3 were relatively low. Therefore, in combination with the differences in maturity of each sample, the 10 varieties of alfalfa were finally divided into three categories, and the varieties of the same series were basically classified into one category. This provides a basis and convenience for future seed screening, identification, traceability and forage breeding.

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Section: Discussionmentioning

confidence: 80%

Analysis and Identification of Differences in Volatile Components of Various Alfalfa Seeds Based on GC-IMS

Zhao,

Zhu,

Yang

et al. 2024

Agronomy

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“…Comprehensive research on the quality of traditional Chinese medicine (TCM) and establishment of the quality standards are deemed as a complicated and systematic task due to its highly complex chemical composition [ 39 , 40 , 41 , 42 ]. The TCM spectrum-effect relationship is an essential tool to determine the safety and efficacy of TCM in use by revealing the interrelationship between the chemical components contained in TCM and the efficacy through the interrelationship between fingerprinting and the efficacy of the medicine [ 43 ].…”

Section: Discussionmentioning

confidence: 99%

Screening out Biomarkers of Tetrastigma hemsleyanum for Anti-Cancer and Anti-Inflammatory Based on Spectrum-Effect Relationship Coupled with UPLC-Q-TOF-MS

Xia

Lin

et al. 2023

Molecules

Self Cite

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Tetrastigma hemsleyanum Diels et Gilg. (T. hemsleyanum) is an economically and medicinally valuable species within the genus Tetrastigma. However, the material basis of its pharmacological action and the biomarkers associated with its anti-cancer and anti-inflammatory effects are still unclear. Additionally, the T. hemsleyanum industry cannot grow because there is a lack of a scientific, universal, and measurable quality control system. This study aimed to explore the chemical basis quality markers related to the anti-cancer and anti-inflammatory effects of T. hemsleyanum to establish an effective quality evaluation method. UPLC-Q-TOF-MSE fingerprint profiles of T. hemsleyanum from different origins were established. Pharmacodynamic studies used HepG2 and HuH-7 cells and LPS-induced RAW264.7 to evaluate the anti-tumor and anti-inflammatory effects of the active ingredients. The spectrum-effect relationships between UPLC fingerprints and anti-cancer and anti-inflammatory activities were evaluated using PCA and PLSR statistical methods. Moreover, docking analysis was performed to identify specific active biomarkers with molecular targets associated with cancer and inflammation. Chlorogenic acid, quinic acid, catechin, kaempferol 3-rutinoside, apigenin-8-C-glucoside, and linolenic acid were associated with anticancer activity, while chlorogenic acid, quercetin, quinic acid, kaempferol 3-rutinoside, rutinum, apigenin-8-C-glucoside, and linolenic acid were associated with anti-inflammatory activity. The spectrum-effect relationship of T. hemsleyanum was successfully established, and the biomarkers for anti-cancer and anti-inflammatory effects were preliminary confirmed. These findings provide a theoretical basis for the elucidation of the substance basis of T. hemsleyanum and lay the foundation for its rapid identification, quality control, industrial research, and utilization.

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“…Spaceflight-induced breeding has long been perceived as an effective way to produce new species with high quantity and excellent quality, and this idea has been enforced by many successful cases of staple crops, such as maize ( Zea mays ) ( Rhoades, 1950 ), rice ( Oryza sativa ) ( Yu et al, 2013 , Zeng et al, 2021 ), wheat ( Triticum aestivuml ) ( Tripathy et al, 1996 ), soybean ( Glycine max) ( Levine et al, 2001 ), rape ( Brassica campestris ), and cotton ( Gossypium hirsutum ). Research has also been launched in medicinal plants and great progresses have been made in Scutellaria baicalensis ( Shan et al, 2008 ), Platycodon grandiflorum ( Wang et al, 2004 ), Carthamus tinctorius ( Gao et al, 1997 ), Glycyrrhiza uralensis ( Wang et al, 2009 ), and Andrographis paniculata ( Xia et al, 2021 ). The mutations induced by spaceflight often emerge in morphology, DNA and chromosomal integrity, and physiological and biochemical properties.…”

Section: Discussionmentioning

confidence: 99%

Variation of photosynthesis, secondary metabolites and antioxidant activities in third generation of spaceflight-induced Salvia miltiorrhiza

Peng

Liang

2022

Chinese Herbal Medicines

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Spaceflight breeding could improve the volatile constituents of Andrographis paniculata

Cited by 15 publications

References 19 publications

Analysis and Identification of Differences in Volatile Components of Various Alfalfa Seeds Based on GC-IMS

Analysis and Identification of Differences in Volatile Components of Various Alfalfa Seeds Based on GC-IMS

Screening out Biomarkers of Tetrastigma hemsleyanum for Anti-Cancer and Anti-Inflammatory Based on Spectrum-Effect Relationship Coupled with UPLC-Q-TOF-MS

Variation of photosynthesis, secondary metabolites and antioxidant activities in third generation of spaceflight-induced Salvia miltiorrhiza

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