Spatial confinement of multi-enzyme for cascade catalysis in cell-inspired all-aqueous multicompartmental microcapsules

Qu, Qi-Xing; Zhang, Xiaoli; Yang, Anquan; Wang, Jing; Cheng, Wei-xia; Zhou, Aying; Deng, Yankang; Xiong, Ranhua; Huang, Chaobo

doi:10.1016/j.jcis.2022.06.128

Cited by 48 publications

(10 citation statements)

References 26 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Furthermore, the study unveiled that disruption of the energy transfer processes was responsible for the behavior of the proportional luminescent probe. The dissimilar decline rates in lifetimes when titrating pure Eu-ZMOF, pure Tb-ZMOF (as shown in Figure S8, Table S3 and Table S4), and mixed Eu 0.479 Tb 0.521 -ZMOF suggested interference by l -NE with energy transfers both from the ligand to metal and from Tb 3+ to Eu 3+ . − …”

Section: Results and Discussionmentioning

confidence: 98%

Zeolite-Like Ln-MOF Luminescent Nanosensor for Highly Efficient Detection of l-Noradrenaline

Fang,

Jiang,

Zhou

et al. 2024

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

L-Noradrenaline (L-NE) is a neurotransmitter released by postganglionic neurons in the sympathetic nerve branch and stimulates the secretion of L-NE in human blood. Accurate monitoring of the L-NE concentration in serum is crucial for detecting stimulants and preventing fraud in competitive events. In this study, we introduce an approach for the detection of L-NE using a zeolite-like lanthanide metal−organic framework (Ln-MOF) named Eu 0.479 Tb 0.521 -ZMOF, constructed with a H 2 bpdc ligand (where H 2 bpdc stands for 2,2′-bipyridine-6,6′-dicarboxylate acid), and forming a nanorod. Notably, the ratiometric luminescent probe Eu 0.479 Tb 0.521 -ZMOF showcases superior sensing performance compared to single emission based on Ln-MOF, enabling highly efficient detection of L-NE among various antidepressant hormones. The limit of detection (LOD) for L-NE was 129 μM. Additionally, Eu 0.479 Tb 0.521 -ZMOF has been synthesized into nanorods, which promote effective detection of L-NE in human serum solutions, exhibiting an impressive recovery rate ranging from 97.5 to 100%. Additionally, a luminescent membrane, derived from Eu 0.479 Tb 0.521 -ZMOF, was successfully developed and utilized for visual detection of L-NE. In conclusion, our study comprehensively elucidates the detailed detection mechanism for L-NE based on zeolite-Like Ln-MOFs Eu 0.479 Tb 0.521 -ZMOF.

show abstract

Section: Results and Discussionmentioning

confidence: 98%

Zeolite-Like Ln-MOF Luminescent Nanosensor for Highly Efficient Detection of l-Noradrenaline

Fang,

Jiang,

Zhou

et al. 2024

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

show abstract

“…Therefore, it is necessary to develop novel strategies to improve the stability of biomass‐based catalytic microreactors, such as delignification pretreatment, coating polymers materials on the microchannel walls, or developing multicompartmental protective structures. [ 58–62 ]…”

Section: Resultsmentioning

confidence: 99%

“…Therefore, it is necessary to develop novel strategies to improve the stability of biomass-based catalytic microreactors, such as delignification pretreatment, coating polymers materials on the microchannel walls, or developing multicompartmental protective structures. [58][59][60][61][62] Intermittent Operating Conditions: Intermittent operation is also important for catalyst lifetime and stability. [63] Catalytic hydrogenation was studied under intermittent operation conditions; 12 h on, followed by four cycles of 12 h off and 12 h on.…”

Section: Long-term Stability Of Pd-tio 2 /B Cmrmentioning

confidence: 99%

Ultrafine Pd Nanoparticles Encapsulated in Mesoporous TiO₂ Region Selectively Confined in Bamboo Microchannels: An Ultrastable Continuous‐Flow Catalytic Hydrogenation Microreactor

Yao

et al. 2023

Small Structures

View full text Add to dashboard Cite

Plant‐based flow microreactors with natural channel structures, renewable properties, and environmental friendliness have increasingly gained popularity in heterogeneous catalysis. However, firmly immobilizing the catalysts simultaneously with ease and adaptability, maintaining great effectivity and long‐term stability, is still a fundamental challenge. Herein, a highly efficient and ultrastable bamboo‐based catalytic microreactor (CMR) containing mesoporous TiO2 (M‐TiO2)‐encapsulating ultrafine Pd nanoparticles (NPs) is constructed for the continuous‐flow hydrogenation of nitroaromatics. The fabrication of the Pd‐TiO2 catalysts in required bamboo microchannels (Pd‐TiO2/B CMR) mainly involves a two‐step region‐selective synthetic strategy with ultra‐low chemical usage, fast preparation, and low catalyst loading (0.007 wt%). The M‐TiO2 films: 1) provide abundant oxygen vacancies and enough open cavities to facilitate the growth of Pd NPs; 2) improve Pd dispersion and reduce particle size; 3) allow diffusion of reactants, and 4) induce strong metal‐support interactions for enhanced catalytic activity and stability. The optimized Pd‐TiO2/B CMR demonstrates high efficiency (>97%) and excellent stability (1,000 h) for the continuous‐flow hydrogenation of nitroaniline, even under intermittent operation (12 h on/12 h off for five cycles) or in a real aqueous matrix (>200 h), making it a promising candidate for Pd‐catalyzed hydrogenation.

show abstract

“…3 Due to the prominent advantages such as high specificity, accuracy, and mild side effects, phototherapy and enzyme cascade-involving cancer treatments have been proven to be effective for TNBC treatment in preclinical research. [3][4][5][6][7][8][9] Phototherapy, including photothermal therapy (PTT) and photodynamic therapy (PDT), is a noninvasive strategy to locally treat tumors at the desired nidus. [10][11][12] However, hyperthermia-based PTT often up-regulates the expression of heat shock proteins such as HSP90, which may generate thermal resistance and thus compromise PTT effects.…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Glycolysis inhibition for synergistic phototherapy of triple-negative breast cancer

Fu,

Bai,

Xue

et al. 2023

J. Mater. Chem. B

View full text Add to dashboard Cite

show abstract

Spatial confinement of multi-enzyme for cascade catalysis in cell-inspired all-aqueous multicompartmental microcapsules

Cited by 48 publications

References 26 publications

Zeolite-Like Ln-MOF Luminescent Nanosensor for Highly Efficient Detection of l-Noradrenaline

Zeolite-Like Ln-MOF Luminescent Nanosensor for Highly Efficient Detection of l-Noradrenaline

Ultrafine Pd Nanoparticles Encapsulated in Mesoporous TiO₂ Region Selectively Confined in Bamboo Microchannels: An Ultrastable Continuous‐Flow Catalytic Hydrogenation Microreactor

Glycolysis inhibition for synergistic phototherapy of triple-negative breast cancer

Contact Info

Product

Resources

About

Spatial confinement of multi-enzyme for cascade catalysis in cell-inspired all-aqueous multicompartmental microcapsules

Cited by 48 publications

References 26 publications

Zeolite-Like Ln-MOF Luminescent Nanosensor for Highly Efficient Detection of l-Noradrenaline

Zeolite-Like Ln-MOF Luminescent Nanosensor for Highly Efficient Detection of l-Noradrenaline

Ultrafine Pd Nanoparticles Encapsulated in Mesoporous TiO2 Region Selectively Confined in Bamboo Microchannels: An Ultrastable Continuous‐Flow Catalytic Hydrogenation Microreactor

Glycolysis inhibition for synergistic phototherapy of triple-negative breast cancer

Contact Info

Product

Resources

About

Ultrafine Pd Nanoparticles Encapsulated in Mesoporous TiO₂ Region Selectively Confined in Bamboo Microchannels: An Ultrastable Continuous‐Flow Catalytic Hydrogenation Microreactor