Spatiotemporal and meteorological trends in dengue transmission in the Dominican Republic, 2015-2019

Abstract

Dengue has broadened its global distribution substantially in the past two decades, and many endemic areas are experiencing increases in incidence. The Dominican Republic recently experienced its two largest outbreaks to date with 16,836 reported cases in 2015 and 20,123 reported cases in 2019. With this upward trend in dengue transmission, developing tools to better prepare healthcare systems and mosquito control agencies is of critical importance. Before such tools can be developed, however, we must first better understand potential drivers of dengue transmission. To that end, we focus in this paper on determining trends between climate variables and dengue transmission with an emphasis on eight provinces and the capital city of the Dominican Republic in the period 2015-2019. We present summary statistics for dengue cases, temperature, precipitation, and relative humidity in this period, and we conduct an analysis of correlated lags between climate variables and dengue cases as well as correlated lags among dengue cases in each of the nine locations. We find that the southwestern province of Barahona had the largest dengue incidence in both 2015 and 2019. Among all climate variables considered, lags between temperature variables and dengue cases were the most highly correlated. We found that most locations had significant correlations at lags of zero weeks; however, both Barahona and the northern province of Monte Cristi had significantly correlated lags with other provinces at up to eight weeks. These results can be used to improve predictive models of dengue transmission in the country.

Multiplicative Mixed-Effects Modelling of Dengue Incidence: An Analysis of the 2019 Outbreak in the Dominican Republic

“…Additionally, variations in average temperature (Temp.avg) have the greatest effect on dengue cases. These results are in agreement with similar studies that found significant risk of dengue when considering lags in climate variables of 2-5 weeks [3,4]. Our findings provide a better understanding of the relationships between meteorological conditions and weekly trends in dengue cases during the outbreak that occurred in the Dominican Republic in 2019.…”

“…One country where dengue has long been endemic is the Dominican Republic. In the past decade, however, dengue outbreaks have grown in incidence, with the 2019 outbreak being the largest outbreak in the country to date [3,4]. In fact, 2019 was the year in which the WHO recorded the highest number of global dengue cases ever to occur within a year [1], suggesting that dengue in the Dominican Republic is mirroring global trends.…”

Codetection of Plasmodium falciparum in Children Hospitalized With Dengue Fever in the Dominican Republic

“…2 In comparison, there were ≈1300–1500 dengue cases in the prior 2 years in the Dominican Republic. 7…”