Comprehensive morphological and mineralogical studies of atmospheric microparticles sampled on the roof of the museum complex and near roads in the town of Istra, Moscow region, have been carried out. Morphological research at different hierarchical levels revealed the multicomponent composition of microparticles and made it possible to identify the most characteristic groups of microparticles of natural and anthropogenic origin. The composition of the studied atmospheric microparticles is dominated by mineral grains of quartz and feldspars; biotite and calcite are singly noted, which reflects the ecological and geographical conditions of their formation, namely the Central Russian mineralogical province. A small share of technogenic particles in the composition of aerosol fallout indicates a low level of technogenic load and a favorable environmental situation in the study area, largely due to the protective functions of the forest park zone. The results of determining the material composition and calculating the enrichment factors also indicate a low level of technogenic impact on the natural environment.