Special report on maladie du coït or dourine

Abstract

Feb. 17th. I'-'^T. rntranniscular inoculation, left shoulder, with 10 c.c. of blood from the general rirciilation of Marc :ii!. a few drops were also inoculated ben(>ath the vrginal mucoumembrane at the-ame time. March 10. Xo swelling has occured since inoculation. The vaginal inucoum embrane apjiears slightly ie(!<'inatous and congested. Micrc'Scopic examinations hav.} been made as follows :-NovemIxT 1 1.-Peripheral blnod-Negative. December 11.-.lugular blond ; vaginal mucus-Negative. .January 15.-Vaginal inueius-Negative. F' brnary 27.-Vajiinal blixid-Negative. !March 7.-Vaginal blood-N.gutive. March 12.-Vaginal blood-Negative. May 13.-The whole of the vaginal mucous membrane is very nnwdi swollen and (ideuiatou.s. tninslucent, of an orange tint, with a few small hiemorrhagic spots and papules. Trypanosomata observed in preparations from l;,e nuieous membrane on this date, and, sidisennently. on May 27 and October 11, May 27.-.Mucous membrane still more (edematous with prominent infiltrated patches. DepigmcTited spots appear along muco-cutaneous margin of vulva, their surfaces rough and ' frosted ' or suggestive of a ground-glass surface. In micro-prepar-ation< from these latter lesions numerous spirocha'tie were observed.