Wood decay have the greatest impact on in-service wood structural elements. In most cases, decay is associated with excessive accumulation of moisture in the wood. The structural design conditions have an effect on the wood moisture content and this affects the service life of the material. In this study, which involved an experimental trial specifically designed to embrace different structural design conditions, the moisture content evolution in different places affected by different design conditions was evaluated over a period of three years in Madrid (Spain). The effect of protection by eaves, separation from the ground and the vertical or horizontal arrangement of the wood elements on the monthly evolution of the moisture content and decay risk are assessed.