Specific frequency bands of amplitude low-frequency oscillation encodes personality

Abstract

The biological model of extraversion and neuroticism identified by Eysenck has stimulated increasing interest in uncovering neurobiological substrate of the two fundamental dimensions. Here we aim to explore brain disturbances underlying extraversion and neuroticism in 87 healthy individuals using fractional amplitude of low-frequency fluctuations (LFF) on resting-state functional magnetic resonance imaging. Two different frequency bands, Slow-5 (0.01-0.027 Hz) exhibiting higher power and involving larger brain regions, and Slow-4 (0.027-0.073 Hz) exhibiting less power and emerging locally, were analyzed. Our results showed a positive correlation between LFF amplitude at Slow-5 and extraversion in medial prefrontal cortex and precuneus, important portions of the default mode network, thus suggesting a link between default network activity and personality traits. LFF amplitude at Slow-5 was correlated positively with neuroticism in right posterior portion of the frontal lobe, further validating neuroticism with frontal lateralization. In addition, LFF amplitude at Slow-4 was negatively associated with extraversion and neuroticism in left hippocampus (HIP) and bilateral superior temporal cortex (STC) respectively, supporting the hypothesized (inverse) relationship between extraversion and resting arousal, also implying neural circuit underlying emotional process influencing on personality. Overall, these findings suggest the important relationships, between personality and LFF amplitude dynamic, depend on specific frequency bands.

Functional neuroimaging of extraversion-introversion

“…In addition, Slow-4 is more reliable and has greater test-retest reliability than Slow-5. A previous study has demonstrated a positive correlation between Slow-5 and extraversion in the midline core regions of the DMN [45] . In contrast, Slow-4 is negatively associated with extraversion in the lef t hippocampus, implying that the neuronal circuitry of emotion infl uences personality traits [45] .…”

“…Slow-4 and Slow-5 have been identified as the primary ships with specific properties such as extraversion [44,45] .…”

Different neural pathways linking personality traits and eudaimonic well-being: a resting-state functional magnetic resonance imaging study

“…Previous studies have shown that extraversion is correlated with the rs-fMRI signal in the STG (Kumari, Williams, & Gray, 2004;Wei et al, 2014) and the thalamus (Kumari et al, 2004). Moreover, task-based fMRI studies have demonstrated that extraversion predicts the STG activity during humor appreciation (Mobbs, Hagan, Azim, Menon, & Reiss, 2005) and the thalamus activity in response to happy faces (Suslow et al, 2010).…”

Frequency of Spontaneous BOLD Signal Differences between Moderate and Late Preterm Newborns and Term Newborns

“…These discoveries may reflect the fact that individual frequency bands could be associated with specific properties (Buzsaki and Draguhn 2004). To date, the two frequency bands (slow-5 and slow-4) have been widely used in rs-fMRI studies when detecting the frequency distribution of spontaneous LFFs in BOLD signals of the human brain (Han et al 2011;Hou et al 2014;Wei et al 2014;Zhang et al 2013;Zuo et al 2010). Here, we aimed to explore the frequency distribution of spontaneous LFFs at specific frequency bands in MLPT newborns for the two different bands (slow-4 and slow-5).…”