Spectrophotometric detection of histidine and lysine using combined enzymatic reactions

Turn-on and blue-shift fluorescence sensor toward l-histidine based on stable CdII metal–organic framework with tetranuclear cluster units

“…7 It is imperative to find an effective and convenient method in bio-chemistry, medicine and clinical research for His analysis due to the significance of His detection. [8][9][10] Until now, plenty of ways to detect amino acids including chromatography, capillary electrophoresis, electrochemistry have been explored. 11 However, time-consuming preparation processes, modification steps, and instability due to environmental factors are common disadvantages of these methods.…”

“…7 It is imperative to find an effective and convenient method in biochemistry, medicine and clinical research for His analysis due to the significance of His detection. 8–10…”

A New Pyrroloquinoline-Derivative-Based Fluorescent Probe for the Selective Detection and Cell Imaging of Lysine

“…Thus, the development of analytical methods for the detection of lysine is of significance for medical and biological research. Some analytical techniques have been used to detect lysine, including colorimetric method [11][12][13][14], liquid chromatography [15] and thin-layer chromatography [16], mass spectrometry [17], luminescent sensors [18], amperometric biosensors [19,20], electrochemical detection [21][22][23][24], and fluorescent probes [25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43]. In these methods, fluorescent probes feature high sensitivity and selectivity-satisfactory capability compared with other complicated methods-having been studied by more researchers.…”

Intriguing pH-modulated Luminescence Chameleon System based on Postsynthetic Modified Dual-emitting Eu3+@Mn-MOF and Its Application for Histidine Chemosensor

“…For example, when taking in excessive His proteins, the intake will cause an important influence on advanced liver cirrhosis. His is also a biomarker to diagnose asthma involved by multiple cells and cell components. , On the basis of the significance of His, it is urgent to explore an effective analytical method of His in biochemistry, medicine, and clinical research. − To date, many analytical methods, including high-performance liquid chromatography, electrochemistry, capillary electrophoresis, mass spectrometry, and colorimetry, ,− are explored in many applications. The employed techniques above, however, are also expensive with regard to their facilities, complicated sample pretreatment, and time-consuming processes .…”