Sperm preservation by electroejaculation in adolescent cancer patients

Gat, Itai; Toren, Amos; Hourvitz, Ariel; Raviv, Gil; Band, Gili; Baum, Micha; Lerner‐Geva, Liat; Inbar, Rotem; Madgar, Igael

doi:10.1002/pbc.24752

Cited by 27 publications

(6 citation statements)

References 29 publications

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“…One of the unfortunate complications of cancer treatment is infertility (3). Unlike adolescents (4) and adults, semen cryopreservation before gonadotoxic exposure is not possible for boys, because spermatogenesis does not commence until puberty (5). This has led to worldwide initiatives to develop spermatogonial stem cell (SSC)-based strategies for fertility preservation.…”

mentioning

confidence: 99%

Optimal culture conditions are critical for efficient expansion of human testicular somatic and germ cells in vitro

Gat

Maghen

Filice

et al. 2017

Fertility and Sterility

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mentioning

confidence: 99%

Optimal culture conditions are critical for efficient expansion of human testicular somatic and germ cells in vitro

Gat

Maghen

Filice

et al. 2017

Fertility and Sterility

Self Cite

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“…This requires coordination with operating room and laboratory staff. It is more often used in patients who have failed PVS and is considered next-line therapy [ 68 ]. It can often be performed in the same anesthetic setting as additionally required oncologic procedures with minimal morbidity [ 69 ].…”

Section: Fertility Preservation In Pubertal or Adolescent Boysmentioning

confidence: 99%

Pediatric and Adolescent Oncofertility in Male Patients—From Alpha to Omega

Bîcă

Sârbu

Ciongradi

2021

Genes

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This article reviews the latest information about preserving reproductive potential that can offer enhanced prospects for future conception in the pediatric male population with cancer, whose fertility is threatened because of the gonadotoxic effects of chemotherapy and radiation. An estimated 400,000 children and adolescents aged 0–19 years will be diagnosed with cancer each year. Fertility is compromised in one-third of adult male survivors of childhood cancer. We present the latest approaches and techniques for fertility preservation, starting with fertility preservation counselling, a clinical practice guideline used around the world and finishing with recent advances in basic science and translational research. Improving strategies for the maturation of germ cells in vitro combined with new molecular techniques for gene editing could be the next scientific keystone to eradicate genetic diseases such as cancer related mutations in the offspring of cancer survivors.

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“…In post‐pubertal patients with cancer who cannot ejaculate due to neurological or psychological problems, electro‐ejaculation is a safe and feasible procedure …”

Section: What Types Of Fp Are Available?mentioning

confidence: 99%

Oncofertility—An emerging discipline rather than a special consideration

Anazodo

Ataman

Jayasinghe

et al. 2018

Pediatric Blood & Cancer

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Originally absent from the oncologist's consult, then placed in a 'quality of life' rubric, oncofertility should now be an essential part of a comprehensive cancer treatment plan in patients of reproductive age, including adolescents and young adults (AYAs). Oncofertility encompasses the endocrine health of the patient, as well as fertility management options. Thus, pubertal transitions in males and females, bone health, and menstrual health are all part of this discipline, enabling practitioners to work in interdisciplinary teams to solve problems in reproductive health. This review provides a summary of the essential considerations required for the assessement of reproductive risk and choice of fertility preservation options as well as considerations for developing oncofertility services for AYAs.

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Sperm preservation by electroejaculation in adolescent cancer patients

Abstract: EEJ is a safe and feasible procedure for cryopreservation in adolescent cancer patients who are unable to masturbate. The wide diversity of EEJ outcome and ejaculate parameters may represent a continuum of pubertal changes in that population.

Cited by 27 publications

References 29 publications

Optimal culture conditions are critical for efficient expansion of human testicular somatic and germ cells in vitro

Optimal culture conditions are critical for efficient expansion of human testicular somatic and germ cells in vitro

Pediatric and Adolescent Oncofertility in Male Patients—From Alpha to Omega

Oncofertility—An emerging discipline rather than a special consideration

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