1991
DOI: 10.1017/s002221510011792x
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Sphenoid sinus mucocoele: a possible late complication of radiotherapy to the head and neck

Abstract: A case of sphenoid sinus mucocoele following radiotherapy in a patient with nasopharyngeal carcinoma is reported. Diagnosis was made by radiological investigation and confirmed at surgery performed via a sublabial transeptal approach. Its content was completely removed and continuous drainage of the sinus was maintained by an indwelling tube. It is felt that the sphenoid mucocoele developed as a result of occlusion of the sinus ostium by scarred mucosa following radiotherapy.

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Cited by 19 publications
(10 citation statements)
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“…Scarring of the mucosa after irradiation may cause occlusion of the sinus ostium, which leads to formation of mucocele (10). Sphenoidal sinus mucoceles developing after radiotherapy for NPC have been reported rarely.…”
Section: Discussionmentioning
confidence: 99%
“…Scarring of the mucosa after irradiation may cause occlusion of the sinus ostium, which leads to formation of mucocele (10). Sphenoidal sinus mucoceles developing after radiotherapy for NPC have been reported rarely.…”
Section: Discussionmentioning
confidence: 99%
“…In the 2 patients with a contrast-enhancing sphenoid sinus mass, there was no large bony defect in the sphenoid sinus floor, thereby preventing any decompression into the nasopharynx, and in both cases the sphenoid sinus showed progressive expansion (Fig 6). Simple mucoceles have been reported previously as a complication of radiation therapy for nasopharyngeal carcinoma [6][7][8][9] and are believed to result from obstruction by scar tissue. It is postulated that the expansion of the sphenoid sinus in this study was caused by ongoing chronic inflammatory and radiation changes obstructing the sinus ostium.…”
Section: Discussionmentioning
confidence: 99%
“…[3][4][5] Rarely a mucocele may form in the sphenoid sinus. 6 However, there are some patients who go on to develop severe delayed radiation effects resulting in the formation of unusual nonmalignant polyps and masses (NMPMs) in the nasopharynx and sphenoid sinus. These radiation-induced injuries cause both clinical and radiologic problems with distinction from recurrent cancer, as well as being a cause of serious morbidity and even mortality.…”
mentioning
confidence: 99%
“…Submucosal oedema may result from allergic rhinitis causing ostia narrowing with obstruction; ostia obstruction may also be due to chronic sinusitis, polyposis, or both [50]. Sphenoid sinus mucocele formation has been reported as a possible late complication of radiotherapy to the head and neck [51] . Radiation causes scarred mucosa which may occlude the sinus ostium.…”
Section: Sphenoid Sinus Mucocelesmentioning
confidence: 99%