Spider’s Silk as a Potential Source of Antibiotics: An Integrative Review

Schwenck, Lucas da Costa; Abreu, Paula Alvarez; Nunes-da-Fonseca, Rodrigo

doi:10.1007/s12602-024-10241-3

Probiotics & Antimicro. Prot.

2024

DOI: 10.1007/s12602-024-10241-3

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Spider’s Silk as a Potential Source of Antibiotics: An Integrative Review

Lucas da Costa Schwenck,

Paula Alvarez Abreu,

Rodrigo Nunes-da-Fonseca

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Harnessing the Potential of Spider Silk Proteins for Biomedical Applications: from Native Silk Fibers to Designed Bioactive Materials

Fang,

Li,

Kou

et al. 2024

Adv Funct Materials

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Spider silk has only been used anecdotally throughout human history, owing to limited supply from natural sources and recalcitrance toward biochemical functionalization. Recent advances in materials synthetic biology have ameliorated the challenges of mass‐producing spider silk and have thus paved the way for reengineering and redesigning these materials for real‐world applications. Here, an update is presented on the development of biomaterials comprising spider silk proteins within the past five years and the respective chemical and genetic approaches behind these developments. Potential applications are further highlighted in areas such as 3‐dimension (3D) cell culturing, drug delivery, theranostics, wound healing, tissue engineering, anti‐infection, and so on. By providing some glimpses into the latest innovations centered around spider silk proteins, as well as the challenges facing their biomedical applications, it is hoped that this will inspire more translational studies of these materials for real‐world impact.

show abstract

Harnessing the Potential of Spider Silk Proteins for Biomedical Applications: from Native Silk Fibers to Designed Bioactive Materials

Fang,

Li,

Kou

et al. 2024

Adv Funct Materials

View full text Add to dashboard Cite

show abstract

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Spider’s Silk as a Potential Source of Antibiotics: An Integrative Review

Cited by 1 publication

References 50 publications

Harnessing the Potential of Spider Silk Proteins for Biomedical Applications: from Native Silk Fibers to Designed Bioactive Materials

Harnessing the Potential of Spider Silk Proteins for Biomedical Applications: from Native Silk Fibers to Designed Bioactive Materials

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