Spinal Anaesthesia for Lower Abdominal Surgery: Levobupivacaine versus Racemic Bupivacaine

Kalaria, RomaTejaskumar; Upadhyay, M R

doi:10.7860/jcdr/2018/31422.11327

Cited by 1 publication

(2 citation statements)

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“…Blood pressure and follow up time period studies. 8,11 Also in our study, time to regression to below T10 was also shorter in group-2 and was in accordance to another study where 141-211 minutes was seen when administered with ropivacaine mixture and 154-209 minutes with bupivacaine mixture. 12 In the current study, it was noted that the mean period of motor blockade onset to Bromage score of 1was 4.63 ± 1.22 minutes with bupivacaine and 6.24 ± 1.52 minutes with ropivacaine which means that the ropivacaine mixture resulted in delayed motor block and this was in agreement with previous studies.…”

Section: Discussionsupporting

confidence: 92%

“…This was in accordance to many other studies where similar results were seen with both the mixtures of LA. 10,11 It is also evident from the current study findings, the surgical procedure was completed in less than 1-hour in all the study participants, but the duration of sensory and motor block was close to 3 hours. This prolonged duration may interfere with post-operative assessment and may put the elderly subjects at unnecessary risk of haemodynamic instability.…”

Section: Discussionsupporting

confidence: 57%

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Intrathecal ropivacaine vs bupivacaine in endoscopic urological surgeries: a double blind randomized controlled trial

Kordcal

Kalyanappagol

Rao

et al. 2019

Sri Lankan J Anaesthesiol

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Aims: To compare sensory, motor effects and haemodynamic stability of 2ml intrathecal isobaric ropivacaine (0.75%) with 3ml hyperbaric bupivacaine (0.75%) in patients undergoing endoscopic urological surgery. Study Design: Randomized controlled trial involving 142 patients undergoing transurethral resection of prostate (TURP) and URS (urethroscopy) in a tertiary care hospital, India. Methods and materials: Patients were randomly allocated to, Group 1 (3ml of 0.5% (15mg) hyperbaric bupivacaine) and Group 2 (2ml of 0.75% isobaric ropivacaine(15mg)). Onset and highest level of sensory block, onset and duration of motor block, quality of anaesthesia and muscle relaxation, haemodynamic parameters and adverse effects if any were studied. Statistical analysis used: Unpaired t-test was used to test continuous variables and chi square test/Fisher's exact test for categorical variables. Results: The mean of highest sensory block, 2 segment regression of sensory block and time for sensory level to regress below T10 was significantly more in group 1 compared to group 2 (P<0.05). There was a significant delay of mean time to onset of motor block to Bromage score 1 in group 2(P<0.001). The mean duration of complete motor blockade was significantly more in group 1 (P value <0.001). Hypotension was most commonly seen in group 1. Conclusion: Ropivacaine provides comparable quality of sensory block but has slower onset and significantly shorter duration of motor block compared to hyperbaric bupivacaine.

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Section: Discussionsupporting

confidence: 92%

Section: Discussionsupporting

confidence: 57%