Spinal schistosomiasis

Balliauw, Christophe; Martens, Frederic; Steen, K. Van; Bladt, Olivier; Vanhoenacker, Peter

doi:10.1016/j.ejrex.2009.10.004

Cited by 4 publications

(2 citation statements)

References 7 publications

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“…Studies in S. japonicum have also shown day-to-day variation in stool egg counts and also clustering of eggs within the stool [47,48]. The presence of eggs in the urine or stool can be detected in less than 50% of neuroschistosomiasis patients [26,49,50]. The Helmintex test for detection of schistosome eggs in faeces, through their interaction with paramagnetic beads in a magnetic field, has recently been described [51].…”

Section: Direct Parasitological Methodsmentioning

confidence: 99%

Neuroschistosomiasis

et al. 2011

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Schistosomiasis (bilharzia) is a neglected tropical disease caused by digenetic trematode platyhelminths of the genus Schistosoma. Neuroschistosomiasis is one of the most severe clinical outcomes associated with schistosome infection. Neurological complications early during the course of infection are thought to occur through in situ egg deposition following aberrant migration of adult worms to the brain or spinal cord. The presence of eggs in the CNS induces a cell-mediated Th2-driven periovular granulomatous reaction. The mass effect of thousands of eggs and the large granulomas concentrated within the brain or spinal cord explain the signs and symptoms of increased intracranial pressure, myelopathy, radiculopathy and subsequent clinical sequelae. Myelopathy (acute transverse myelitis and subacute myeloradiculopathy) of the lumbosacral region is the most common neurological manifestation of S. mansoni or S. haematobium infection, whereas acute encephalitis of the cortex, subcortical white matter, basal ganglia or internal capsule is typical of S. japonicum infection. Cerebral complications include encephalopathy with headache, visual impairment, delirium, seizures, motor deficits and ataxia, whereas spinal symptoms include lumbar pain, lower limb radicular pain, muscle weakness, sensory loss and bladder dysfunction. The finding of eggs in the stool or a positive serology, provides supportive but not direct evidence of neuroschistosomiasis. A definitive diagnosis can only be made with histopathological study showing Schistosoma eggs and granulomas. Schistosomicidal drugs (notably praziquantel), steroids and surgery are currently used for the treatment of neuroschistosomiasis. During the 'acute phase' of the disease, neuroschistosomiasis is treated with corticosteroids which are augmented with a course of praziquantel once female worm ovipositioning commences. Surgery should be reserved for special cases such as in those with evidence of medullary compression and in those who deteriorate despite clinical management.

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Section: Direct Parasitological Methodsmentioning

confidence: 99%

Neuroschistosomiasis

et al. 2011

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“…Quando há o contato com água doce contaminada, a cercária penetra na pele do hospedeiro e dirige-se à circulação portal e mesentérica, iniciando a deposição dos ovos (Gryseels, Polman, Clerinx, & Kestens, 2006). Os ovos partem para as veias vertebrais através do plexo avalvular de Batson que possui anastomoses com as veias profundas ilíaca e cava inferior que ligam as veias da pelve e do reto com a medula espinhal (Balliauw, Martens, Steen, Bladt, & Vanhoenacker, 2010;Jongste et al, 2010). Uma reação inflamatória é desencadeada a partir da deposição dos ovos no sistema nervoso central (Silva et al, 2004).…”

Section: Introductionunclassified

Efeitos da gameterapia na mielorradiculopatia esquistossomótica: Relato de caso

Carvalho¹,

Silva²,

Garção³

et al. 2014

Motricidade

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ARTIGO ORIGINAL | ORIGINAL ARTICLE RESUMOA esquistossomose mansônica é uma doença parasitária causada pelo helminto Schistosoma mansoni. A sua forma ectópica mais grave e incapacitante é a mielorradiculopatia esquistossomótica (MRE), caracterizada por atingir o sistema nervoso central. Atualmente, o uso da Realidade Virtual para o tratamento das sequelas de doenças neurológicas vem se desenvolvendo gradativamente. O objetivo deste estudo foi analisar a influência da Realidade Virtual (RV) sobre as funções neuromotoras de uma portadora de MRE. O estudo foi realizado com um indivíduo do sexo feminino, 30 anos de idade, com diagnósti-co clínico de MRE e sem experiência prévia com o Nintendo Wii ® ou similares. O procedimento de avaliação adotado visou à descrição e análise do comprometimento causado pelas afeções da MRE. A paciente foi avaliada, submetida à fisioterapia utilizando o Nintendo Wii ® e a plataforma Wii Balance Board ® que consistiu de 20 sessões com duração de 1 hora e frequência de três vezes por semana; após o tratamento a paciente foi reavaliada. Os resultados demonstraram que para a voluntária em estudo, a RV foi uma ferramenta eficaz na reabilitação neuromotora de MRE. Palavras-chave: terapia assistida por computador, neuroesquistossomose, modalidades de fisioterapia, esquistossomose mansoni ABSTRACT Schistosomiasis mansoni is a parasitic disease caused by Schistosoma mansoni. Its ectopic form most severe and disabling is the Schistosomal Myeloradiculopathy (SMR), characterized by reaching the central nervous system. Currently, the use of Virtual Reality for the treatment of neurological sequelae has been developing gradually. The aim of this study was to analyze the influence of Virtual Reality (VR) on neuromotor functions of a SMR carrier. The study it was carried out with a female subject, 30 years old, diagnosed with SRM and no preview experience with the Nintendo Wii ® or similar. The assessment procedure adopted aimed to describe and analyze the impairment caused by disorders of the MRE. Intervention program included a physical therapy program playing with the Nintendo Wii ® and Wii Balance Board ® platform (20 sessions lasting 1 hour and a frequency of three times per week). Subject was assessed before and after the intervention program. The results showed that the VR was an effective tool in neuromotor rehabilitation of SRM.

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