Splenic artery embolization in the management of an acute immune thrombocytopenic purpura–related intracranial hemorrhage

Puapong, Devin P.; Terasaki, Keith K.; Lacerna, Melinda; Applebaum, Harry

doi:10.1016/j.jpedsurg.2005.02.005

Cited by 9 publications

(11 citation statements)

References 15 publications

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“…9 Splenic artery embolization and recombinant activated factor VII was also used successfully in two different cases having CNS bleeding complicating ITP. 10,11 In our case, the patient was complaining of severe headache, vomiting, semiconsciousness requiring emergency treatment. Surprisingly patient's symptoms completely resolved over a period of 15 days after raising the platelet count.…”

Section: Case Reportmentioning

confidence: 76%

Subarachnoid Haemorrhage Complicating Resistant Idiopathic Thrombocytopenic Purpura: A Case Report

et al. 2014

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Idiopathic thrombocytopenic purpura (ITP) is an autoimmune disease where low platelet counts predisposeto various bleeding tendencies; intracranial haemorrhageis one of them. It is a rare and devastating complication of ITP, mostly presenting as intracerebral (ICH) or subarachnoid haemorrhage (SAH). Here, we report a 32-year-old splenectomized chronic ITP patient on corticosteroid and azathioprine, in whom spontaneous SAH developed. In this case, conservative management resulted in clinicoradiological improvement and showed eventual favourable out-come.Birdem Med J 2014; 4(2): 105-107

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Section: Case Reportmentioning

confidence: 76%

Subarachnoid Haemorrhage Complicating Resistant Idiopathic Thrombocytopenic Purpura: A Case Report

et al. 2014

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“…Puapong et al reported on the successful splenic embolization in a child with intracranial bleeding and persistent thrombocytopenia before neurosurgical management of the intracranial hematoma. 3 From this case it would seem reasonable to embolize the spleen before serious bleeding complications develop. Additionally, Takahashi et al reported their results on five children who had splenic embolization one day before surgical splenectomy.…”

Section: Discussionmentioning

confidence: 94%

Partial Splenic Embolization for Refractory Thrombocytopenia

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2011

Clinics and Practice

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When the platelet count falls below 20×109/L, the risk of spontaneous life threatening hemorrhage is concerning for both physician and patient. When medical management fails, splenectomy is often used to manage the severe thrombocytopenia before spontaneous, life-threatening gastrointestinal or intracranial bleeding occurs. We present the non surgical management of such a patient with refractory sever thrombocytopenia who refused surgical intervention. She underwent partial splenic embolic therapy with 500–700μ particles. Her platelet count spontaneous recovered from less than 20×109/L to normal range. Her counts remained in normal range after discharge home. Further study is needed to determine the most appropriate role for embolization in patients who are refractory to medical management and those with chronically low platelet counts requiring frequent plate transfusions for invasive procedures.

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“…La esplenectomía es una opción razonable cuando el tratamiento con factores de crecimiento, metrotrexato o rituximab fallan y se necesita una rápida mejoría de la pancitopenia/neutropenia [7][8] . La esplenectomía deriva en una rápida mejoría de la neutropenia en la mayoría de los pacientes 6 .…”

Section: Discussionunclassified

Embolización parcial del bazo en el síndrome de Felty

García-Nielsen¹,

Padilla²,

Feldman³

et al. 2014

Rev. Argent. Reumatol.

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El síndrome de Felty comprende la asociación de artritis reumatoidea crónica, neutropenia y esplenomegalia. Esta última, cuando se asocia a hiperesplenismo, se caracteriza por el desarrollo de trombocitopenia, leucopenia, anemia o de todas. La embolización parcial endovascular del bazo puede ser una opción válida para el tratamiento del hiperesplenismo, pero no está exenta de riesgos. Presentamos el caso de un paciente joven, con artritis reumatoidea, síndrome de Felty e hiperesplenismo, a quien se realizó embolización parcial endovascular del bazo.

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Splenic artery embolization in the management of an acute immune thrombocytopenic purpura–related intracranial hemorrhage

Cited by 9 publications

References 15 publications

Subarachnoid Haemorrhage Complicating Resistant Idiopathic Thrombocytopenic Purpura: A Case Report

Subarachnoid Haemorrhage Complicating Resistant Idiopathic Thrombocytopenic Purpura: A Case Report

Partial Splenic Embolization for Refractory Thrombocytopenia

Embolización parcial del bazo en el síndrome de Felty

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