Split-bolus vs. multiphasic contrast bolus protocol in patients with pancreatic cancer or cholangiocarcinoma

Muenzfeld, Hanna; Mahjoub, Samy; Roehle, Robert; Pelzer, Uwe; Bahra, Marcus; Boening, Georg; Hamm, Bernd; Geisel, Dominik; Auer, Timo Alexander

doi:10.1016/j.ejrad.2019.07.027

Cited by 5 publications

(4 citation statements)

References 21 publications

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“…Multidetector computed tomography (MDCT) of the pancreas offers a valuable alternative to magnetic resonance imaging, particularly for patients with contraindications to MRI. It provides advantages such as easier access, high resolution, and the ability to generate multiplanar reconstructions [49,50]. The recommended MDCT pancreatic examination protocol involves dual-phase contrast acquisitions in the pancreatic and portal venous phases using a narrow detector configuration [49,50].…”

Section: Multidetector Computed Tomography (Mdct)mentioning

confidence: 99%

“…It provides advantages such as easier access, high resolution, and the ability to generate multiplanar reconstructions [49,50]. The recommended MDCT pancreatic examination protocol involves dual-phase contrast acquisitions in the pancreatic and portal venous phases using a narrow detector configuration [49,50]. Some institutions utilise the double bolus technique and dual-energy CT systems in MDCT, achieving comparable visualisation of the pancreatic parenchyma and tumours with a lower radiation dose [49,50].…”

Section: Multidetector Computed Tomography (Mdct)mentioning

confidence: 99%

“…The recommended MDCT pancreatic examination protocol involves dual-phase contrast acquisitions in the pancreatic and portal venous phases using a narrow detector configuration [49,50]. Some institutions utilise the double bolus technique and dual-energy CT systems in MDCT, achieving comparable visualisation of the pancreatic parenchyma and tumours with a lower radiation dose [49,50]. Multiplanar reconstructions and maximum intensity projections of 1-3 mm slices aid in detecting duct communication and characterising pancreatic cysts [51,52].…”

Section: Multidetector Computed Tomography (Mdct)mentioning

confidence: 99%

“…In summary, a dual-phase CT examination is recommended for initial assessment, with the option of repeating the dual-phase protocol for monitoring. However, single acquisitions during the early portal vein phase or DECT in the portal vein phase are also considered acceptable options [49,50,53].…”

Section: Multidetector Computed Tomography (Mdct)mentioning

confidence: 99%

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Intraductal Papillary Mucinous Neoplasms (IPMN): Diagnosis, Classification, and Risk Assessment - A Review of Current Medical Knowledge

Otręba,

Cieszkowska,

Czupryńska

et al. 2024

J Educ Health Sport

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Introduction In recent years, the widespread utilisation of advanced imaging modalities has led to a surge in the detection rate of pancreatic cystic lesions, particularly intraductal papillary mucinous neoplasms (IPMN). Consequently, this review aims to provide a comprehensive examination of IPMN, focusing on elucidating its intricate facets including definition, epidemiology, pathogenesis, classification, imaging modalities for diagnosis, analysis of pancreatic cyst fluid, evaluation of malignant potential, and identification of pertinent features. Brief Overview of Current Knowledge: IPMN represents a diagnostic conundrum owing to its variable biological behaviour encompassing both benign and malignant spectra, necessitating meticulous evaluation and risk stratification. Various imaging techniques such as MRI, CT, EUS and abdominal ultrasonography serve pivotal roles in the diagnostic algorithm and risk assessment of IPMN. Additionally, the analysis of pancreatic cyst fluid, incorporating biomarkers and the string sign test, assumes a critical role in discerning mucinous from non-mucinous cysts and gauging malignant potential. Discriminating high-risk stigmata and worrisome features serve as a compass for clinical decision-making regarding the imperative of surgical intervention versus vigilant surveillance. Summary Despite persistent challenges, the ongoing evolution of diagnostic modalities and risk assessment methodologies augur well for refining therapeutic strategies and enhancing clinical outcomes in managing IPMN. This review underscores the imperative of sustained research endeavours in the realm of pancreatic oncology to enrich our comprehension of IPMN pathophysiology and to optimise clinical care paradigms.

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