Spontaneous Pregnancy in Couples Waiting for Artificial Insemination Donor Because of Severe Male Infertility

Matorras, Roberto; Díez, J.; Corcóstegui, Beatriz; Morán, José M.; Pijoán, José Ignacio; Rodriguez-Escudero, F.J.

doi:10.1016/s0022-5347(01)62982-3

Cited by 6 publications

(11 citation statements)

References 0 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Very little could be found in the nineties in English medical literature about oligozoospermic couples achieving pregnancy. Matorras et al. (1996) reported about pregnancies of oligozoospermic couples at the time when these couples were booked for donor insemination: three of 46 (6.5%) had sperm counts of 0.1–1.0 million ml −1 and two of 26 (7.7%) had counts of 1–2 million ml −1 .…”

Section: Discussionmentioning

confidence: 99%

“…(2001) reported on five cases of spontaneous conception after successful or unsuccessful ICSI treatment where the husband was diagnosed repeatedly with severe oligoasthenozoospermia. All cases reported by Matorras et al. (1996); Osmanagaoglu et al.…”

Section: Discussionmentioning

confidence: 99%

“…Paternity tests were performed for oligozoospermic patients included in this study when authorization could be obtained: Matorras et al. (1996) and Osmanagaoglu et al.…”

Section: Discussionmentioning

confidence: 99%

“…(1996) and Osmanagaoglu et al. (1999) reported that no paternity tests were performed in their studies of severe oligozoospermia, but Matorras et al. (1996) reported extra‐marital rates of 30% among patients who were on waiting lists for donor insemination.…”

Section: Discussionmentioning

confidence: 99%

See 3 more Smart Citations

Oligozoospermia: recent prognosis and the outcome of 73 pregnancies in oligozoospermic couples

Zyl

Menkveld

2006

Andrologia

View full text Add to dashboard Cite

The minimum value for each of the five main semen parameters, below which conception rarely occurred or did not occur at all, was calculated in a group of 1884 couples complaining of primary and secondary infertility: 304 conceptions including first as well as consecutive conceptions, occurred. The parameters evaluated were (minimum value calculated in this study between brackets) volume (1.0 ml), sperm count ml(-1) (2.0 million), total sperm count (4.0 million), motility (10%), forward progression (2.0 MacLeod units: scale 1-4) and normal sperm morphology (3%). The pregnancy rate in the group of 308 oligozoospermic men and the minimum value of semen parameters were the cornerstones in determining the prognosis for oligozoospermic patients. A sperm count of >2.0 million ml(-1) was considered relatively adequate for eventual conception judged by the 68 of 308 (22.1%) pregnancies that occurred among oligozoospermic men in this study, provided that the other five semen parameters showed values above the minimum value. In cases where the average sperm count was <2 million ml(-1), the chances for conception became rare, viz five of 308 (1.6%). The total number of pregnancies in the group classified as oligozoospermic was 73 (23.7%). With these pregnancies there was no increase in the rate of foetal wastage and congenital abnormalities. Abortion occurred in 15.09% and ectopic pregnancy in 0.9% among first and consecutive pregnancies. One infant among the 56% boys and 44% girls was born with congenital abnormalities. Most of these infants had a normal birth mass of >2500 g.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“…Paternity tests were performed for oligozoospermic patients included in this study when authorization could be obtained: Matorras et al. (1996) and Osmanagaoglu et al.…”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Oligozoospermia: recent prognosis and the outcome of 73 pregnancies in oligozoospermic couples

Zyl

Menkveld

2006

Andrologia

View full text Add to dashboard Cite

show abstract

“…In summary, oligozoospermia is associated with poor sperm motility and abnormal sperm morphology. It reduces sperm quality and its fertilization capacity, although oligozoospermic men do fertilize naturally at times, even in severe cases (25).…”

Section: Severe Oligozoospermiamentioning

confidence: 99%

Semen analysis in laboratory practice: An overview of routine tests

Andrade-Rocha¹

2003

Clinical Laboratory Analysis

View full text Add to dashboard Cite

Semen analysis is a basic step in the investigation of several disturbances affecting the male genital tract. Analysis of seminal parameters provides important clinical information on the spermatogenesis and functional competence of spermatozoa, as well as on the secretory pattern of the accessory genital glands. Semen analysis is particularly useful in the evaluation of couples requiring fertility investigation (to detect genital infections and pathologies) and in verifying the influence of environmental factors, drugs, lifestyle, chemical products, and professional activities on several diseases affecting male reproductive health. Measure of semen quality is of substantial interest for diagnoses in clinical urology, andrology, and gynecology. Currently, basic requirements for semen analysis are standardized by World Health Organization (WHO) guidelines that describe several procedures for an objective evaluation of the semen quality with diagnostic purposes. These guidelines include: parameters for the physical and biochemical evaluation of semen; parameters for the analysis of sperm characteristics; and other seminal parameters that can be easily adopted in any laboratory. This report summarizes current concepts on semen analysis and the significance of the seminal parameters for reaching a diagnosis based on the procedures recommended by WHO guidelines.

show abstract

Cinnoxicam andl‐Carnitine/Acetyl‐l‐Carnitine Treatment for Idiopathic and Varicocele‐Associated Oligoasthenospermia

Cavallini¹,

Ferraretti²,

Gianaroli³

et al. 2004

Journal of Andrology

147

142

View full text Add to dashboard Cite

The objective of this study was to detect a therapy for idiopathic and varicocele-associated oligoasthenospermia (OAT). Idiopathic and varicocele OAT patients were randomized into 3 groups. Each group was composed of varying degrees of left varicoceles (graded into 5 grades with echo-color Doppler) and of idiopathic OATs. Group 1 used a placebo, group 2 used oral L-carnitine (2 g/d) + acetyl-L-carnitine (1 g/d), group 3 used L-carnitine/acetyl-L-carnitine + 1 x 30-mg cinnoxicam suppository every 4 days. Drugs were administered for 6 months. The groups were composed as follows: group 1, 71 varicoceles and 47 idiopathic OATs; group 2, 62 varicoceles and 39 idiopathic OATs; group 3, 62 varicoceles and 44 idiopathic OATs. Sperm concentration, motility, and morphology before during and after treatments were assessed. Pregnancy rates and side effects were recorded. Group 1 did not have modified sperm patterns during treatment. Group 2 had significantly increased sperm patterns at 3 and 6 months into therapy in idiopathic patients and in patients with grades I, II, and III varicocele, but not in grades IV and V. Group 3 had significantly increased sperm parameters in all patients, with the exception of grade V varicocele. Group 3 sperm patterns proved significantly higher during therapy than group 2. All sperm patterns fell to baseline after therapy suspension. Minor side effects occurred. Pregnancy rates were 1.7% (group 1), 21.8% (group 2), and 38.0% (group 3) (P <.01). L-carnitine/acetyl-L-carnitine + cinnoxicam suppositories proved a reliable treatment for low-grade varicoceles and idiopathic OATs.

show abstract

Spontaneous Pregnancy in Couples Waiting for Artificial Insemination Donor Because of Severe Male Infertility

Cited by 6 publications

References 0 publications

Oligozoospermia: recent prognosis and the outcome of 73 pregnancies in oligozoospermic couples

Oligozoospermia: recent prognosis and the outcome of 73 pregnancies in oligozoospermic couples

Semen analysis in laboratory practice: An overview of routine tests

Cinnoxicam andl‐Carnitine/Acetyl‐l‐Carnitine Treatment for Idiopathic and Varicocele‐Associated Oligoasthenospermia

Contact Info

Product

Resources

About