Spontaneous Rupture of Multiple Extensor Tendons Following Repeated Steroid Injections: a Case Report

Zhang, Bing; Hu, Sheng-ting; Zhang, Yingze

doi:10.1111/j.1757-7861.2012.00170.x

Cited by 15 publications

(16 citation statements)

References 24 publications

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“…The use of corticosteroids, which is another conservative treatment method, has anti-inflammatory effects and causes a temporary reduction in pain, but it may also cause tendon weakening and rupture. Tendon ruptures have been reported in the literature, especially after repeated steroid injections (21)(22)(23). No such complications are observed in kinesiologic taping treatment in our study and in literature.…”

Section: Discussionsupporting

confidence: 55%

Efficacy of Kinesiologic Taping in de Quervain’s Tenosynovitis: Case Series and Review of Literature

Kaçmaz¹,

Koca²,

Basa³

et al. 2019

btd

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Objective: Kinesiologic tapes are used for therapeutic purposes to reduce the pain, improve the bioelectrical activity of the muscles, and to reduce the edema. The repetitive movements of the abductor pollicis longus and extensor pollicis brevis muscles result in pain in wrist. This is called De Quervain tenosynovitis. The aim of this study was to investigate the efficacy of kinesiologic taping as a conservative treatment method for de Quervain's tenosynovitis. Methods: Fifteen patients between 20 and 60 years of age who were treated with kinesiologic taping for De Quervain's tenosynovitis included in the study. The pain and function scores before and after the implementation of kinesiologic taping were gathered from patient files. Pain was measured using the visual analog scale (VAS), and functions were evaluated using the quick disabilities of the arm, shoulder, and hand (Q DASH) score and Michigan Hand Outcomes Questionnaire. The differences between the pre and posttreatment scores were observed to determine the efficacy of kinesiologic taping in the treatment of de Quervain's tenosynovitis. Results: All but three of the 15 patients showed improvement in pain and functional scores (VAS, Q DASH, Michigan). Favorable outcomes were obtained with kinesiologic taping in terms of pain and function scores in 12 out of 15 patients included in our study indicates that kinesiologic taping is a feasible and useful technique in de Quervain's disease. None of the patients suffered from any complications. Conclusion: We pointed that kinesiologic taping is an effective treatment method for de Quervain's tenosynovitis in terms of pain and function with no complication. According to this study kinesiologic taping is a good alternative in the conservative treatment of de Quervain's tenosynovitis.

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Section: Discussionsupporting

confidence: 55%

Efficacy of Kinesiologic Taping in de Quervain’s Tenosynovitis: Case Series and Review of Literature

Kaçmaz¹,

Koca²,

Basa³

et al. 2019

btd

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“…The reduction of all examined collagen subtypes indicates that Dex may lead to a weakening of tendon structure. It is therefore not surprising that spontaneous ruptures have been linked to injections of corticosteroids in tendons [21–28]. Our results give a plausible molecular explanation for that.…”

Section: Discussionmentioning

confidence: 59%

“…Clinical studies on the use of glucocorticoids for tendinopathies have reported short-term pain relief but poor long-term effects including a weakening of tendon structure on the longer perspective [19, 20]. In fact, many reports about spontaneous, often non-traumatic tendon ruptures following the use of these substances have been published [21–28]. …”

Section: Introductionmentioning

confidence: 99%

The tenocyte phenotype of human primary tendon cells in vitro is reduced by glucocorticoids

Spang

Chen

Backman

2016

BMC Musculoskelet Disord

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BackgroundThe use of corticosteroids (e.g., dexamethasone) as treatment for tendinopathy has recently been questioned as higher risks for ruptures have been observed clinically. In vitro studies have reported that dexamethasone exposed tendon cells, tenocytes, show reduced cell viability and collagen production. Little is known about the effect of dexamethasone on the characteristics of tenocytes. Furthermore, there are uncertainties about the existence of apoptosis and if the reduction of collagen affects all collagen subtypes.MethodsWe evaluated these aspects by exposing primary tendon cells to dexamethasone (Dex) in concentrations ranging from 1 to 1000 nM. Gene expression of the specific tenocyte markers scleraxis (Scx) and tenomodulin (Tnmd) and markers for other mesenchymal lineages, such as bone (Alpl, Ocn), cartilage (Acan, Sox9) and fat (Cebpα, Pparg) was measured via qPCR. Cell viability and proliferation was calculated using a MTS Assay. Cell death was measured by LDH assay and cleaved caspase-3 using Western Blot. Gene expression of collagen subtypes Col1, Col3 and Col14 was analyzed using qPCR.ResultsStimulation with Dex decreased cell viability and LDH levels. Dex also induced a significant reduction of Scx gene expression and a marked loss of fibroblast like cell shape. The mRNA for all examined collagen subtypes was found to be down-regulated. Among non-tendinous genes only Pparg was significantly increased, whereas Acan, Alpl and Sox9 were reduced.ConclusionsThese results indicate a Dex induced phenotype drift of the tenocytes by reducing scleraxis expression. Reduction of several collagen subtypes, but not cell death, seems to be a feature of Dex induced tissue degeneration.

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“…5 Closed late ruptures may also derive from iatrogenic causes as intratendinous steroid injections or after some surgical treatments, such as plating distal radius fractures. [6][7][8][9][10] Closed tendon rupture is a rare complication of the Kienböck disease. In this pathological condition, the blood supply to the lunate is interrupted by various causes and results in a progres sive osteonecrosis, with bone deformities at the late stages.…”

Section: Introductionmentioning

confidence: 99%

A Two-Phase Rupture of the Superficial and Profundus Flexor Tendons of the Second Finger of a Hand in a Patient with an Undiagnosed Kienböck Disease

Rosa

Colzani

Duca

et al. 2019

Journal of Hand and Microsurgery

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The authors present an unusual case of a two-phase rupture of the superficial and profundus flexor tendons of the second finger of a hand in a patient with an undiagnosed Kienböck disease. This kind of lesions may be progressive and extend to adjacent tendons in a relatively rapid succession; therefore, they should be treated urgently. The intervention must provide for the removal of the cause of mechanical unbalance or friction before acting on the tendon, thus a radiographic study of the wrist is essential to plan the treatment of any closed rupture of a flexor tendon.

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Spontaneous Rupture of Multiple Extensor Tendons Following Repeated Steroid Injections: a Case Report

Cited by 15 publications

References 24 publications

Efficacy of Kinesiologic Taping in de Quervain’s Tenosynovitis: Case Series and Review of Literature

Efficacy of Kinesiologic Taping in de Quervain’s Tenosynovitis: Case Series and Review of Literature

The tenocyte phenotype of human primary tendon cells in vitro is reduced by glucocorticoids

A Two-Phase Rupture of the Superficial and Profundus Flexor Tendons of the Second Finger of a Hand in a Patient with an Undiagnosed Kienböck Disease

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