Spring-loaded syringe for multiple rapid injections

Abstract

Mesotherapy refers to multiple injections of small quantity of the drug over a large area. The mesoguns available are expensive and the motor-driven models tends to waste the expensive material to be injected since the plunger stops after injecting without recoil. We searched for a less expensive device which would inject like the mesogun and still not waste the solution. On searching the web, we identified a spring-loaded syringe. We describe the assembly and use of this inexpensive syringe for delivering multiple injections with minimal wastage.

A novel needle‐free microjet drug injector using Er:YAG LASER: A completely new concept of transdermal drug delivery system

“…This device utilizes a laser to vaporize cosmetic substances and create pressure from this process to disseminate cosmetic substances into the skin in the form of microjets. Compared to clear holes made by mesotherapy or messogun (Srinivas et al, 2017), the damage to the epidermis is hardly visible to the naked eye in the tissue specimens. This suggests that the laser device minimizes damage to the epidermis.…”

“…The papillary dermis is considered to be the best target for injection of cosmetic materials because it is a layer where esthetic effects, such as collagen stimulation, can be maximized (Srinivas et al, 2017; Zhou et al, 2020). The laser device penetration was at a depth of 300um, which is the upper part of the dermis.…”

“…Compared to the manually performed injections, the needle injector performs more regular and accurate injections. (Srinivas et al, 2017) There remain a few problems; however, as the injection is as slow and painful as when manually performed. Nevertheless, with no suitable alternatives, physicians prefer the use of such injection devices.…”

Needleless laser injector versus needle injection for skin enhancement and rejuvenation effect of dermal filler

“…Therefore, they still have drawbacks such as limited range of jet volume that can be injected, low injection velocity, inaccurate injection depth, significant pain due to tissue dissection, and long downtime (Online Supporting Information: Table S1). 1,[5][6][7] There has been growing interest on needleless injectors that use laser energy. 8,9 Mirajet (JSK Biomed) was the first laser-induced microjet injector to acquire Conformité Européenne certification for medical devices in the European Union, and this device uses an Er:YAG laser that generates vapor bubbles to generate pressure energy.…”

“…Although these methods allow for more stable and accurate injections than manual injection techniques, there are still limitations owing to the restricted adjustability of the amount of input energy during the injection of the target material. Therefore, they still have drawbacks such as limited range of jet volume that can be injected, low injection velocity, inaccurate injection depth, significant pain due to tissue dissection, and long downtime (Online Supporting Information: Table ) 1,5–7 …”