2015
DOI: 10.1016/j.amjoto.2015.01.012
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Squamous cell carcinoma in a thyroglossal duct cyst: A case report with review of the literature

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Cited by 28 publications
(24 citation statements)
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“…Other possible explanations proposed regarding the origin of papillary carcinomatous lesions in thyroglossal remnants include multi focal origin of carcinomas in genetically predisposed individuals and metastasis from papillary carcinomas of thyroid gland [16]. Columnar lining of the thyroglossal cyst can undergo metaplasia and lead to squamous cell carcinoma on rare instances [4] even in the absence of thyroid tissue in the ductal epithelial lining and surrounding soft tissue of the thyroglossal cyst. Therefore, some researchers believe that squamous cell carcinoma is the only true carcinoma of the thyroglossal cyst [17,18].…”
Section: Discussionmentioning
confidence: 99%
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“…Other possible explanations proposed regarding the origin of papillary carcinomatous lesions in thyroglossal remnants include multi focal origin of carcinomas in genetically predisposed individuals and metastasis from papillary carcinomas of thyroid gland [16]. Columnar lining of the thyroglossal cyst can undergo metaplasia and lead to squamous cell carcinoma on rare instances [4] even in the absence of thyroid tissue in the ductal epithelial lining and surrounding soft tissue of the thyroglossal cyst. Therefore, some researchers believe that squamous cell carcinoma is the only true carcinoma of the thyroglossal cyst [17,18].…”
Section: Discussionmentioning
confidence: 99%
“…Adjuvant radiotherapy is recommended in case of positive surgical margins, extensive nodal metastasis and larger tumour size [4].…”
Section: Discussionmentioning
confidence: 99%
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“…Review of literature has revealed 25 reported cases of squamous cell carcinoma of the thyroglossal duct cyst till date. [1] …”
Section: Introductionmentioning
confidence: 99%
“…This carcinoma can appear during the childhood, but the peak incidence is between the forth and the fifth decades, females are affected slightly more often than males, with a 3:2 ratio [8]. The papillary hystotype is about 80% of all the thyroglossal carcinomas, followed by mixed folliculo-papillary carcinoma (8%), squamocellular carcinoma (6%) and the remaining 6% concerns Hurtle cells carcinoma, follicular carcinoma and anaplastic carcinoma [9] [10] [11]. …”
Section: Introductionmentioning
confidence: 99%