“…More than 100 HPV genotypes have already been described so far and, among these, 24 genotypes have been associated with oral lesions (HPV-1, 2, 3,4,6,7,10,11,13,16,18,30,32,33,35,45,52,55,57,59, 69, 72 e 73) (5). Terai et al (1999) in a PCR-based study on HPV prevalence highlighted the presence of HPV 18 in a normal mucous membrane, suggesting that the oral cavity may be a virus reservoir and that the association with other factors, such as alcohol and smoking, could induce the appearance of lesions (6).…”