A field experiment was conducted at College Farm, Agricultural College, Rajendranagar, Hyderabad, during kharif 2019-20 and 2020-21 to study the effect of genotypes and integrated nutrient management practices on growth of HDPS cotton. Experiment was laid out in Split plot design, with two genotypes as main plots (M) and nine Integrated Nutrient Management practices as sub-plots (S). Among genotypes, Leaf Area Index (LAI), Absolute Growth Rate (AGR), Relative Growth Rate (RGR), Net Assimilation Rate (NAR) were recorded with Bt (KCH-14 K59 BG II) compared to Non-Bt (ADB-542) during kharif 2019-20 and 2020-21. Among integrated nutrient management treatments, significantly higher LAI, AGR, RGR, NAR were observed with 100% RDF + soil application Jeevamrutha @ 500 L ha-1 at 15 days interval up to harvest (S5) during both years and which was comparable with 100 % RDF + Foliar spray of Jeevamrutha @ 5% at 15 days interval up to harvest (S7) and 100 % RDF (S3), respectively. Finally, Bt cotton had recorded LAI, AGR, RGR, NAR than non Bt. Among integrated nutrient management practices, S5 had recorded maximum LAI, AGR, RGR, NAR.