St Elevation Myocardial Infarction in Elderly and Very Elderly Patients

Montisci, Roberta; Cacace, Cristina; Congia, Michela; Marchetti, Maria Francesca; Scotto, Riccardo; Caddeo, Piero; Meloni, Luigi

doi:10.1016/s0735-1097(18)30741-1

Cited by 2 publications

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“…In our study, there was no significant difference between the time from symptom onset to admission of surviving and deceased patients, but both groups had very late presentation for STEMI treatment with a mean time delay of 14.7 ± 28.6 hours. The delay to STEMI treatment was very well apprecited medical issue and independent predictor of in-hospital mortality [19].…”

Section: Discussionmentioning

confidence: 98%

“…However, atypical symptoms like dyspnea, nausea and syncope [18,2] may be one of the reason for a delay of elderly patients' arrival to the hospital. It has been shown that the time from onset of symptoms to hospital admission of these patients was prolonged compared to younger patients [2,18], measured as first medical contact time and total ischemic time (p < 0.001) [16,19]. Schoenenberger et al [20] found that the delay from symptom onset to hospital admission of patients ≥ 70 years decreased between 2001 and 2012 in acute myocardial infarction in Switzerland (AMIS) cohort.…”

Section: Discussionmentioning

confidence: 99%

“…Still, STEMI network is less efficient in elderly than younger patients [19], as they received both thrombolytic and invasive procedures less frequently when compared with younger patients [1,23,30]. However, recent registries observed trend of increase rate of aggressive treatment of STEMI in elderly, especially PPCI [8,20,30].…”

Section: Discussionmentioning

confidence: 99%

“…In Serbia, as in most developing countries, there is a trend of population aging and the proportion of patients over 65 years has increased from 8.9% in 1971 to 19.2% of population in 2016. In last decades, cardiovascular diseases were the leading cause of mortality in Serbia with 51.7% of all deaths in 2016, and 17.5% due to ischemic heart disease (about 50% from acute coronary syndrome) [5].…”

Section: Introductionmentioning

confidence: 99%

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Clinical characteristic and management of elderly patients with myocardial infarction

et al. 2019

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Introduction/Objective Population of elderly people is increasing and modern medicine is faced with the problem of large morbidity and mortality from cardiovascular diseases in this age group. Modern treatment strategies have not been sufficiently investigated in the elderly, therefore these people often receive suboptimal treatment. The aim of the study was to evaluate clinical characteristic, cardiac risk factors, management strategies and early outcome in the elderly patient with ST elevated myocardial infarction (STEMI). Methods This retrospective study included 217 consecutive patients, aged ≥ 70 years (mean age 77.6 ± 4.9 years, 103 men, 114 women) with STEMI admitted to the Institute of Cardiovascular Diseases of Vojvodina. We have analyzed patients' clinical characteristics, risk factors, left ventricular function and treatment strategies in relation to in-hospital outcome. Results First clinical symptom was chest pain in 209 (96.3%) of patients. On admission, 35 (16.1%) patients were with severe signs of heart failure (Killip class III-IV). Duration of symptom onset to hospital admission was 14.7 ± 28.6 hours. Out of 217 patients, 168 (77.4%) patients received reperfusion treatment, including primary percutaneous coronary ntervention (PPCI) in 164 (75.6%) patients, and fibrinolytic therapy in 4 (1.8%) patients. Hospital mortality was 26.3% (57 patients). PPCI was univariate predictor of lower in-hospital mortality, whereas multivariate predictors of in-hospital mortality were cardiogenic shock (OR 67.095; 95% CI (6.845-657.646); p < 0.001) and low ejection fraction (OR 0.901; 95% CI (0.853-0.963); p = 0.001). Conclusion In elederly patients presenting with STEMI, PPCI was asscoiated with lower mortality, whereas cardiogenic shock and lower ejection fraction were independent predictors of worse prognosis after STEMI.

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Section: Discussionmentioning

confidence: 98%

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Clinical characteristic and management of elderly patients with myocardial infarction

et al. 2019

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“…Близько 80 % випадків цього невідкладного стану зустрічається в осіб віком понад 60 років [5]. Окрім того, у низці досліджень відзначено, що в літніх пацієнтів проміжок між виникненням симптомів і початком коронарної реваскуляризації довший, ніж у хворих віком до 60 років [6,7].…”

Section: вступunclassified

Кардиопротекторный Эффект Нитроглицерина При Неотложной Чрескожной Эндоваскулярной Реваскуляризации Миокарда У Пациентов Пожилого Возраста С Острым Коронарным Синдромом

Furkalo¹,

Лоскутов²,

Dziuba³

et al. 2021

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Кардіопротективний ефект нітрогліцерину при невідкладній черезшкірній ендоваскулярній реваскуляризації міокарда в пацієнтів похилого віку з гострим коронарним синдромом Резюме. Актуальність. У 2018 році в США ішемічна хвороба серця була причиною летальних випадків у 43,8 % хворих і посіла лідируюче місце у структурі смертності від патології серцево-судинної системи. Золотим стандартом невідкладної допомоги при гострому коронарному синдромі (ГКС) вважається ендоваскулярна реваскуляризація коронарних артерій. Суттєвим ускладненням навіть технічно коректної процедури може стати ішемічно-реперфузійне ураження міокарда. Однією з груп препаратів, що застосовуються з метою кардіопротекції, є нітрати, найпоширеніший з яких-нітрогліцерин. Не має одностайної думки щодо доцільності та ефективності використання цього препарату з метою кардіопротекції через його переважний вплив на венозне судинне русло та розвиток толерантності при тривалому введенні. Мета: дослідити ефективність кардіопротективного ефекту нітрогліцерину у хворих похилого віку з ГКС під час ендоваскулярної реваскуляризації міокарда.

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St Elevation Myocardial Infarction in Elderly and Very Elderly Patients

Cited by 2 publications

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Clinical characteristic and management of elderly patients with myocardial infarction

Clinical characteristic and management of elderly patients with myocardial infarction

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