Stability and Effectiveness of Laser and Liquiband Treatments in the Rat Model of Oral Ulcer

Kang, Ji Won; Ryu, Hyun Seok; Abueva, Celine; Chung, Phil‐Sang; Woo, Seung Hoon

doi:10.25289/ml.2021.10.4.207

Cited by 4 publications

(2 citation statements)

References 16 publications

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“…PBM limits the production of proinflammatory mediators, including tumor necrosis factor-α (TNF-α), Interleukin-1 (IL-1), IL-1β, and IL-6 in damaged neurons, inhibits prostaglandins E2 and increases the production of plasminogen, as well as stimulates post-traumatic maturation and regeneration. 19,22,[26][27][28] In addition, PBM can increase tissue microcirculation/oxygenation and stimulate the growth of epithelial, endothelial, and mesenchymal cells. 29 Enhanced tissue microcirculation can lead to an increase in the delivery of nutritional substances related to the elevated mitosis rate, resulting in neoangiogenesis.…”

Section: Discussionmentioning

confidence: 99%

Effectiveness of Photobiomodulation in Reducing Pain of Oral Mucosal Diseases: A Case Series

Santoso¹,

Sufiawati²

2023

IMCRJ

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Pain management becomes important in the treatment of oral mucosal diseases since it can impair the quality of life. Photobiomodulation (PBM) as an alternative therapy, has potency in reducing pain through several mechanisms targeting peripheral nerves in the target tissue. Purpose: To discuss the effectiveness of PBM in the management of four cases of oral mucosal diseases. Case: Four patients, two females and two males, with an age ranging from 24 to 63 years came to the Oral Medicine Department complaining of painful lesions in their oral cavity. Three cases showed ulceration of the oral mucosa and had been diagnosed with recurrent aphthous stomatitis, recalcitrant chronic ulcer, and non-specific chronic sialadenitis. One patient who complained of intense pain and swelling on the right side of the face was diagnosed with post-herpetic neuralgia (PHN). Case Management: PBM was administered in all four cases (976 nm diode laser, three cases with spot size 0.01 cm 2 , fluency 10 J/cm 2 , and one case with spot size 0.5 cm 2 ; fluency 3 J/cm 2 ). Visual analog scale (VAS) control was performed before and after the PBM at each visit. The recorded VAS results show a reduction in pain that started at the post-laser time, with VAS before PBM ranging from 5 to 7 and after PBM ranging from 0 to 4. Three patients were given triamcinolone acetonide 0.1%, chlorhexidine gluconate 0.2% mouthwash, petroleum jelly, and multivitamins. One patient was given mefenamic acid and multivitamins. Conclusion: PBM can be a useful adjunctive treatment to relieve the pain of oral mucosal diseases due to its ability to reduce pain intensity.

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Section: Discussionmentioning

confidence: 99%

Effectiveness of Photobiomodulation in Reducing Pain of Oral Mucosal Diseases: A Case Series

Santoso¹,

Sufiawati²

2023

IMCRJ

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“…First, PBM delivers photons to the mitochondria of the cell. Delivered photon energy is absorbed by cytochrome c oxidase which is the last electron transportation chain that mediates electron transfer from cytochrome c to molecular oxygenation, resulting elevation of ATP and ROS concentration [26][27][28]. These increased mitochondrial activities cause interplay with the nucleus of the cell which translates to modifying the gene expression related to dense tissue formation and ossification [4,27,29].…”

Section: Photobiomodulation Therapy For Bone Regenerationmentioning

confidence: 99%

Application of photobiomodulation therapy in the recovery of a fracture model in different countries: a concise review

Kim

Padalhin²

2022

Medical Lasers

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The bone is a dynamic biological tissue composed of metabolically active cells which are integrated into a hard framework. However, it can be injured due to trauma or infections and this can result in bone defects. Hence, bone generation or bone healing has been an interesting field of orthopedics and has been the subject of multiple studies. As a result, various substances which promote osteogenesis and angiogenesis have been identified, but their mechanism of action has not yet been completely elucidated. Owing to its anti-inflammatory and wound-healing effects, photobiomodulation (PBM) has been proposed in the treatment of various disease conditions. Specifically, in orthopedics, multiple studies have been conducted to treat bone generation or bone union using PBM. The clinical improvement of bone healing as well as various substances and mechanisms of osteogenesis and angiogenesis by PBM have been identified although the mechanism of action is not fully understood. This review summarizes the published reports on the bone healing effects of PBM treatment in fracture sites.

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Photobiomodulation Therapy in the Treatment of Salivary Dysfunction

Abueva¹

2022

Medical Lasers

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Stability and Effectiveness of Laser and Liquiband Treatments in the Rat Model of Oral Ulcer

Cited by 4 publications

References 16 publications

Effectiveness of Photobiomodulation in Reducing Pain of Oral Mucosal Diseases: A Case Series

Effectiveness of Photobiomodulation in Reducing Pain of Oral Mucosal Diseases: A Case Series

Application of photobiomodulation therapy in the recovery of a fracture model in different countries: a concise review

Photobiomodulation Therapy in the Treatment of Salivary Dysfunction

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