1965
DOI: 10.1002/jps.2600540135
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Stability of Methicillin

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Cited by 20 publications
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“…Methicillin is very unstable in acid (143,144), and its decomposition is roughly 2-3 times faster than that of phenethicillin. The reactions, in general, are very dependent on pH and have a much narrower stability zone near a pH of 6.5.…”
Section: Reactions Of the 3-carboxyl Group In Penicillins-mentioning
confidence: 99%
“…Methicillin is very unstable in acid (143,144), and its decomposition is roughly 2-3 times faster than that of phenethicillin. The reactions, in general, are very dependent on pH and have a much narrower stability zone near a pH of 6.5.…”
Section: Reactions Of the 3-carboxyl Group In Penicillins-mentioning
confidence: 99%