Stage effect of chronic kidney disease in erectile function

Costa, Maria Alice Nunes; Ponciano, Viviane Campos; Costa, Théo Rodrigues; Gomes, C P; Oliveira, Ênio Chaves de

doi:10.1590/s1677-5538.ibju.2017.0228

Cited by 11 publications

(10 citation statements)

References 32 publications

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“…10 In a Brazilian study of 245 patients with chronic renal failure, relationship between serum albumin levels and IIEF score was found. 11 A similar relationship was also confirmed in a multinational study of 945 patients receiving hemodialysis. 12 Additionally, in a Taiwanese study of 453 outpatients with diabetes, serum albumin in patients without ED and overactive bladder was significantly higher than in those with ED and/or overactive bladder.…”

Section: Discussionsupporting

confidence: 54%

Serum albumin levels as a useful complementary marker for erectile dysfunction in ulcerative colitis: A cross‐sectional study

Yamamoto,

Furukawa,

Miyake

et al. 2023

Int J of Urology

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ObjectiveRecently, a close association between ulcerative colitis (UC) and erectile dysfunction (ED) was reported. An inverse relationship between serum albumin and ED is found in patients with chronic disease. However, the association between serum albumin levels and ED in patients with UC is unclear. This study aims to investigate this issue in Japanese patients with UC.MethodsOne hundred and thirty‐six Japanese male UC patients were enrolled in this study. Information on serum albumin levels and medications for UC from medical records, Sexual Health Inventory for Men (SHIM) score information from self‐administered questionnaires and information on the severity of UC from physician reports were obtained from medical records, self‐administered questionnaires, and reports from physicians. The participants were divided into tertiles based on the total protein, serum globulin, serum albumin, aspartate aminotransferase, and C‐reactive protein levels. The definition of ED and severe ED was SHIM score < 22 and SHIM score < 8, respectively. The association between these serum markers and ED was assessed by multivariate logistic regression.ResultsThe prevalence of severe ED in the low, moderate, and high albumin groups was 66.0%, 51.0%, and 28.3%, respectively. After adjusting for confounding factors, the low albumin group was independently and positively associated with severe ED (adjusted odds ratio: 2.74, 95% confidence interval: 1.03–7.48, p for trend =0.044). No association between other marker and ED was found.ConclusionSerum albumin was independently inversely associated with severe ED in Japanese patients with UC. Hypoalbuminemia might be a useful complementary marker for assessing the prevalence and severity of ED in UC patients.

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Section: Discussionsupporting

confidence: 54%

Serum albumin levels as a useful complementary marker for erectile dysfunction in ulcerative colitis: A cross‐sectional study

Yamamoto,

Furukawa,

Miyake

et al. 2023

Int J of Urology

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“…Antonucci M showed a similar prevalence of 71% in a study that compared ED in hemodialysis patients and patients undergoing kidney transplantation [33]. According to Costa M 81.1% of chronic kidney patients grades 4 or 5 had some level of ED, using the questionnaire and hormonal dosage [34].…”

Section: Discussionmentioning

confidence: 90%

Hypogonadism and erectile dysfunction in patients with chronic kidney disease undergoing hemodialysis

Maciel¹,

Oliveira²,

Chaves³

et al. 2023

World J. Adv. Res. Rev.

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Objective: To know the profile of Hypogonadism and Erectile Dysfunction (ED) in patients with chronic kidney disease (CKD) on hemodialysis studied. Method: The case-control study was the Case group, consisting of patients with CKD on hemodialysis (INEFRO) and the Control group by patients under outpatient follow-up. The Androgenic Deficiency in Aging Males (ADAM) and International Index of Erectile Function (IIEF) questionnaires were applied, and the following clinical examinations were performed: orchidometry, analysis of hair distribution, gynecomastia and BMI. Results: ADAM’s mean score was 4.2 points (case) and 1.9 points (control). In the Case group 60% have observed decreased libido and 70% perceived that the erections are less vigorous. In the Control group, prevalence decreased to 30% in both questions. In the analysis of IIEF-5, the mean score was 16.63 (case) and 19.93 (control). 60% of patients in the Case group and 50% of the Control group have some degree of ED. Gynecomastia was evaluated in 20% (case) and 7% (control). The orchidometry of the Case group revealed prevalence in 53.33% of testicular volume 3 patients of the orchidometer. In the control group, the most prevalent measure was 4, found in half of the patients (50%). Conclusions: Through the questionnaires applied in both groups with similar mean ages, it can be inferred that patients in the Case group experienced earlier, throughout the dialysis process, a direct impact on sexual quality, with decreased libido and difficulty in the reaction when compared to the Control group.

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“…The results of Banks et al [ 22 ] strongly support previous findings indicating that men with erectile dysfunction require assessment for cardiovascular disease risk, including ischemic heart disease, stroke, and peripheral vascular disease. There is a clear association of erectile dysfunction and cardiovascular diseases, while the endothelium dysfunction occurring in cardiovascular diseases may contribute to the pathogenesis of dysfunction [ 23 ]. We found an independent association between cardiovascular diseases and erectile dysfunction in the group of patients who died.…”

Section: Discussionmentioning

confidence: 99%

Survival of Patients on Hemodialysis with Erectile Dysfunction

et al. 2020

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Background and objectives: In patients on hemodialysis, erectile dysfunction is an independent mortality factor. This study aimed to determine the risk factors that affect the survival of hemodialysis patients with erectile dysfunction. Materials and Methods: During a seven-year period, erectile dysfunction was identified among the fatalities reported in patients receiving chronic hemodialysis, on the basis of the International Index of Erectile Function questionnaire. The study covered 70 patients of mean age 57 ± 6.7 years. During the examined period, 42 (60%) patients died at the mean age 57 ± 6.8 years. The study was completed by 28 (40%) patients, aged 57 ± 6.55 years. Laboratory, demographic, anthropometric, and clinical characteristics were recorded using standard methods. Results: Statistically significant differences between the two groups of respondents were found concerning dialysis duration (p < 0.001), number of leukocytes (p = 0.003), adequacy of hemodialysis (p = 0.004), intima media thickness of the carotid artery (p < 0.001), presence of cardiovascular disease (p = 0.03), residual diuresis (p = 0.04), and hemodiafiltration (p < 0.001). Hemodialysis adequacy (B = −9.634; p = 0.017), intima media thickness (B = 0.022; p = 0.003), residual diuresis (B = −0.060; p = 0.007), and lower rates of cardiovascular disease (B = 0.176; p = 0.034) were significant survival predictors among our patients with erectile dysfunction. Conclusions: Risk factors that are associated with improved survival of patients on hemodialysis with erectile dysfunction in our study are: preserved diuresis, high-quality hemodialysis, lower incidence of cardiovascular disease, and less thickening of the intima media of the carotid arteries.

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Stage effect of chronic kidney disease in erectile function

Cited by 11 publications

References 32 publications

Serum albumin levels as a useful complementary marker for erectile dysfunction in ulcerative colitis: A cross‐sectional study

Serum albumin levels as a useful complementary marker for erectile dysfunction in ulcerative colitis: A cross‐sectional study

Hypogonadism and erectile dysfunction in patients with chronic kidney disease undergoing hemodialysis

Survival of Patients on Hemodialysis with Erectile Dysfunction

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