Staged-surgery with permanent pathology for the management of high-risk nonmelanoma skin cancer of the nose

Eskıızmır, Görkem; Gençoğlan, Gülsüm; Temız, Peyker; Hırçın, Zafer; Ermertcan, Aylin Türel

doi:10.1007/s00405-010-1324-x

Cited by 11 publications

(6 citation statements)

References 23 publications

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“…In addition, in some previous studies, SEPMC has been performed in either low- and high-risk BCCs or specific areas such as the nose or periorbital area. 7 , 8 , 9 …”

Section: Discussionmentioning

confidence: 99%

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Outcome of staged excision with pathologic margin control in high-risk basal cell carcinoma of the head region

Kavoussi

Ebrahimi

et al. 2020

Anais Brasileiros de Dermatologia

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Background High-risk basal cell carcinoma involves a significant rate of basal cell carcinoma that requires Mohs micrographic surgery for definitive treatment. Staged excision with pathologic margin control is a simple, accessible, and curative procedure suggested for the treatment of high-risk basal cell carcinoma. Objective To evaluate the results of staged excision of high-risk basal cell carcinoma in the head region. Methods This interventional study was performed on patients with high-risk basal cell carcinoma, who underwent staged excision until the margins were free of tumor. Results A total of 122 patients (47 females and 75 males) with mean age of 57.66 ± 9.13 years were recruited in this study. Nasal and nodular types were the most common of both clinical and pathologic forms, respectively. Further, 89.3 % of cases were cured by staged excision after four years of follow-up. There was a significant relationship between treatment outcomes and recurrent lesions, multiplicity of risk factors, long-standing disease, and pathologic type. There was also a significant association between the number of surgical excisions and multiplicity of risk factors, as well as recurrence, location, and size of basal cell carcinoma. Study limitations Lack of magnetic resonance imaging assessment in cases of suspected perineural invasion. Conclusions High-risk basal cell carcinoma had a high cure rate by staged excision. Patients with more risk factors and those with nasal and recurrent basal cell carcinoma required more staged excisions. Failure of treatment is more probable in patients with more risk factors, long-standing lesions, and high-risk pathologic and recurrent basal cell carcinomas.

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“…In addition, in some previous studies, SEPMC has been performed in either low- and high-risk BCCs or specific areas such as the nose or periorbital area. 7 , 8 , 9 …”

Section: Discussionmentioning

confidence: 99%

“…Staged excision with pathologic margin control (SEPMC) is a simple and accessible procedure with a high cure rate that is suggested for the treatment of special types of BCC or for special sites such as periorbital or nasal areas. 6 , 7 , 8 , 9 , 10 …”

Section: Introductionmentioning

confidence: 99%

Outcome of staged excision with pathologic margin control in high-risk basal cell carcinoma of the head region

Kavoussi

Ebrahimi

et al. 2020

Anais Brasileiros de Dermatologia

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“…It is known that the presence of vital structures in the head and neck region and the difficulty of identifying tumor boundaries due to sun exposure require careful consideration of surgical margins in skin cancers. In relation to this clinical challenge, we have reported there liable role of "staged surgery" for the reduction of local recurrences in high-risk non-melanoma skin cancers [19] . Furthermore, Moyer et al concluded that staged tumor resection was an effective and useful technique and decreased local recurrences in cutaneous malignant melanoma of the head and neck [20] .…”

Section: What Is the Surgical Margin For Cutaneous Malignant Melanomamentioning

confidence: 99%

Current Treatment Strategies in Cutaneous Malignant Melanoma of the Head and Neck

Özgür¹,

Karakullukçu²,

Eskıızmır³

2019

ENT Updates

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Cutaneous malignant melanoma is potentially an important health problem for white people. The incidence of melanoma is rising faster than other solid cancers. Despite the new melanoma drugs surgery for localised melanoma and regional metastasis is still the standard of care. However management of cutaneous melanoma differs from other cancers at some points such as biopsy technique , surgical margine, incorporation ofsentinel lymph node biopsy for staging etc. In this review we focused on the role of the head and neck surgeon in management of cutaneous melanoma of head and neck region according to current knowledge.

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“…The tumorous processes of the skin increase patient worries and thus addressing frequencies by primary care services, dermatology, plastic surgery. Typically, concern relates to the patient on the cosmetic appearance and on the malignant potential of the lesion [3,4]. Knowing the most common forms of benign and malignant skin tumours is crucial for a proper evaluation and therapeutic management.…”

Section: Introductionmentioning

confidence: 99%

Clinical and histo-pathological aspects of the skin tumours in the nasal region

Aftenie¹,

Bordeianu

2016

ARS Medica Tomitana

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Nasal pyramid presents an increased frequency of skin tumours such as basal cell or squamous cell carcinomas. That could be explained by the increased rate of solar radiation exposure. Fear of a malign skin disease have been rising public awareness of the danger of exposure to sunlight. However, the incidence of skin cancer is continuously increasing. The probability of developing a skin tumour increases with age. Typically, concern relates to the patient on the cosmetic appearance and on the malignant potential of the lesion. Nasal defects can take place most often after oncological procedures. Knowing the most common forms of benign and malignant skin tumours is crucial for a proper evaluation and therapeutic management. Particular importance should be given to those clinical issues that may raise suspicion of a malignant lesions turn. In this study we evaluated the incidence of nasal pyramid tumours. This included also the pathological aspect of nasal skin.

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Staged-surgery with permanent pathology for the management of high-risk nonmelanoma skin cancer of the nose

Cited by 11 publications

References 23 publications

Outcome of staged excision with pathologic margin control in high-risk basal cell carcinoma of the head region

Outcome of staged excision with pathologic margin control in high-risk basal cell carcinoma of the head region

Current Treatment Strategies in Cutaneous Malignant Melanoma of the Head and Neck

Clinical and histo-pathological aspects of the skin tumours in the nasal region

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