Staged tendon grafts and soft tissue coverage

Elliot, David

doi:10.4103/0970-0358.85354

Cited by 12 publications

(14 citation statements)

References 17 publications

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“…The authors reported an unsatisfactory range of motion at the MCP joint in six out of 14 patients. This indicates that the tunnels created by the rods provide better tendon gliding, and this has been observed in two-staged flexor tendon reconstruction (Elliot, 2011). (2000) 1 Groin flap Flexor superficialis tendon transfer 15° extension lag, 30° limitation of flexion Bevin and Hothem (1978) 2…”

Section: Discussionmentioning

confidence: 93%

Two-staged extensor tendon reconstruction for zone 6 extensor tendon loss of the fingers: indications, technique and results

Al‐Qattan

2013

J Hand Surg Eur Vol

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Over a 20-year period, six patients (19 tendons) underwent two-staged extensor tendon reconstruction using silicone rods followed by palmaris longus tendon grafts sutured proximally to the divided flexor carpi radialis tendon. All patients were young men (mean age, 22 years) who sustained the injury in car accidents. The soft tissue loss from the dorsum of the hand was associated with extensor tendon loss over the entire zone 6 with or without loss in zone 7. Primary soft tissue coverage was done elsewhere, and patients presented for secondary tendon reconstruction. All patients had supple metacarpophalangeal joints before reconstruction. After the two-staged tendon reconstruction, full or near-full active flexion at the metacarpophalangeal joints was obtained in all patients. However, minor extension lags (10°-15°) at the metacarpophalangeal joints were seen in 15 out of 19 reconstructed fingers.

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Section: Discussionmentioning

confidence: 93%

Two-staged extensor tendon reconstruction for zone 6 extensor tendon loss of the fingers: indications, technique and results

Al‐Qattan

2013

J Hand Surg Eur Vol

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“…Grafting of flexor and extensor tendons of the hand is especially challenging since restoration of function and dexterity require both a strong repair and effective gliding. 42 Tendon autografts and allografts are also used in anterior cruciate ligament reconstruction, which is often more successful than direct repair. Autografts are preferred to allografts due to better tissue integration, recellularization, and revascularization; however, donor site morbidity can be significant.…”

Section: The Clinical Importance Of Tendon and Ligament Bioreactorsmentioning

confidence: 99%

A brief history of tendon and ligament bioreactors: Impact and future prospects

Dyment

Barrett

Awad

et al. 2020

Journal Orthopaedic Research

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Bioreactors are powerful tools with the potential to model tissue development and disease in vitro. For nearly four decades, bioreactors have been used to create tendon and ligament tissue-engineered constructs in order to define basic mechanisms of cell function, extracellular matrix deposition, tissue organization, injury, and tissue remodeling. This review provides a historical perspective of tendon and ligament bioreactors and their contributions to this advancing field. First, we demonstrate the need for bioreactors to improve understanding of tendon and ligament function and dysfunction. Next, we detail the history and evolution of bioreactor development and design from simple stretching of explants to fabrication and stimulation of two-and three-dimensional constructs. Then, we demonstrate how research using tendon and ligament bioreactors has led to pivotal basic science and tissue-engineering discoveries. Finally, we provide guidance for new basic, applied, and clinical research utilizing these valuable systems, recognizing that fundamental knowledge of cell-cell and cell-matrix interactions combined with appropriate mechanical and chemical stimulation of constructs could ultimately lead to functional tendon and ligament repairs in the coming decades.

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“…Originally, upon examination of the autoacceleration of the conversion-time curves, it was believed that termination reaction only became diffusion controlled at some monomer conversion greater than zero [28] and that this occurred when the polymer chains were sufficiently entangled (with a sufficient number of physical entanglement points). [25] Besides that, Hamielec and Tobita [25] stated that the bimolecular termination reactions may be diffusion controlled even at zero monomer conversion.…”

Section: Resultsmentioning

confidence: 99%

“…Originally, upon examination of the autoacceleration of the conversion–time curves, it was believed that termination reaction only became diffusion controlled at some monomer conversion greater than zero and that this occurred when the polymer chains were sufficiently entangled (with a sufficient number of physical entanglement points)…”

Section: Resultsmentioning

confidence: 99%

Autoacceleration and Cyclization Effects on Styrene/Divinylbenzene Copolymerization

Santos

Aguiar

Giudici

2016

Macromol. React. Eng.

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Copolymerizations of styrene with divinylbenzene (DVB) are carried out at low monomer concentrations in order to evaluate the incidence of cyclization reactions. The pendant double bond concentration in the synthesized polymers is measured using Fourier transform infrared spectroscopy. Reactions are carried out at monomer concentrations of 6% and 2% (v/v), DVB concentration in the range 15–80 wt% and temperatures in the range 60–90 °C. A previously developed model is used to interpret the results and analyze the cyclization effects. The predictions of the model accounting for cyclization reactions present a better agreement to the experimental data in comparison to predictions without cyclizations. Autoacceleration effects are observed for cases with higher DVB concentrations, in which the formation of highly entangled structures may have occurred. The model provides an estimate of 0.05 for the crosslink parameter (CP) and 130 s−1 for the rate constant of cyclization for the smallest sequence (three units) at 90 °C.

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Staged tendon grafts and soft tissue coverage

Cited by 12 publications

References 17 publications

Two-staged extensor tendon reconstruction for zone 6 extensor tendon loss of the fingers: indications, technique and results

Two-staged extensor tendon reconstruction for zone 6 extensor tendon loss of the fingers: indications, technique and results

A brief history of tendon and ligament bioreactors: Impact and future prospects

Autoacceleration and Cyclization Effects on Styrene/Divinylbenzene Copolymerization

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