Standardized uptake value for 18F-fluorodeoxyglucose is correlated with a high International Prognostic Index and the presence of extranodal involvement in patients with Diffuse Large B-Cell Lymphoma

Prognostic value of interim fluorodeoxyglucose and fluorothymidine PET/CT in diffuse large B-cell lymphoma

“…Numerous studies have demonstrated the potential prognostic value of interim FDG PET/CT, utilizing measures including the maximum (mean) standardized uptake value [SUV max (mean)], ΔSUV max , metabolic tumor volume, and total lesion glycolysis. [3][4][5] These interim PET/CT indexes have been compared with the International Prognostic Index (IPI), 6 which is a widely accepted clinical prognostic index for patients with aggressive lymphomas. The correlation between SUV and IPI may indicate pretreatment FDG uptake as a metabolic marker for the prognosis of DLBCL patients.…”