In this paper, we consider the problem of array design for Multiple-Input Multiple-Output (MIMO) array under the condition of fixed number of physical sensors and mutual coupling. A novel MIMO array based on the second-order super nested transmit and receive arrays is proposed by using the difference coarray. It can obtain the closed form expressions for the physical sensor locations and the degrees of freedom (DOF) from any given number physical sensors. The proposed array structure can significantly enhance DOF and effectively decrease unknown mutual coupling effect. The effectiveness and superiority of the proposed MIMO array structure are verified from the number of DOF and MUSIC spectra by numerical simulations.