Staphylococcus Aureus Cellulitis: An Unusual Presentation

Abstract

Staphylococcus aureus has long been known as one of the most virulent microbes, with capabilities that make it threatening in both nosocomial and community-acquired infections. It remains the most frequent cause of skin-structure and traumatic infections in the community. S. aureus infections in the maxillofacial region are likely to be associated with a known portal of entry, but this is not always the case. Once invasion occurs, the organism may produce virulent enzymes including coagulase, hyaluronidase, proteases, DNA-ase, lipases, hemolysins, and lysozyme as well as exotoxins. Markel et al point out that cellulitis associated with coagulase-positive staphylococci will often resolve without abscess formation. Hence, there is often no site from which to obtain specimens, making this infection a diagnostic and therapeutic challenge. This report describes an infection in which the etiologic organism was identified as S. aureus. The source of the infection, however, remained unclear.

Isolated Idiopathic Lip Abscess: A Case Report

“…Because of this reason, prior to culture and sensitivity results, empirical antibiotic treatment must be chosen to target those organism known to be more frequently infectious in this region. 3,6 Therefore we gave to our patient intravenous ampicillin and sulbactam as empirical antibiotic therapy before the result of culture. Infections in these regions have classically been treated with penicillins, but resistant organisms have developed due to its long and widespread use.…”

“…Lip swelling decreased on the fifth day of treatment (Figure 2). Body temperature came to normal and the peripheral white blood cell count decreased to 9000 cells per mm 3 . The patient was discharged on the sixth day without any complaint.…”

“…There were no palpable cervical lymph nodes. The peripheral white blood cell count was 18,400 cells per mm 3 , with 63% segmented neutrophils. Human immunodeficiency virus serology was negative.…”

“…Gram-positive aerobic pathogens, Haemophilus influenza, anaerobic pathogens may also cause these infections. [1][2][3] Pathogen of the infection that causes facial abscess vary by location and source of the infection. 4 The classic signs of maxillofacial infections are pain, swelling, fever, dysphagia and dehydration.…”

Our natural “makeup” reveals more than it hides: Modeling the skin and its microbiome

“…S. aureus cause a wide spectrum of infections. In the skin, this ranges from atopic dermatitis (Byrd et al, 2017; Kobayashi et al, 2015), hair follicle infections (Ibler & Kromann, 2014), and subcutaneous infections (Geunes, Brooks, Huttula, & Chesney, 1994). They can also penetrate into any organ in the body and lead to potentially fatal conditions like sepsis (Naber, 2009), osteomyelitis (Olson & Horswill, 2013), and endocarditis (Hoerr et al, 2018).…”