Staphylococcus aureus – Review on potential targets for sensors development

Tătaru, Alexandru; Canciu, Alexandra; Tertiş, Mihaela; Cristea, Cécilia; Cernat, Andreea

doi:10.1016/j.bioelechem.2023.108492

Cited by 7 publications

(2 citation statements)

References 53 publications

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“…Detecting bacteria is not always sufficient. Many bacterial pathogens, such as S. aureus, E. coli, C. botulinum, C. perfringens, C. difficile, B. cereus, C. jejuni, L. monocytogenes, Yersinia enterocolitica, and Salmonella spp., produce toxins [181][182][183][184][185][186][187][188][189]. Ingested bacteria toxins have various effects, ranging from disrupting cell membranes and causing cell death to interfering with the host immune response.…”

Section: Other Aptasensors For Bacterial Detectionmentioning

confidence: 99%

Recent Advances in Aptamer-Based Biosensors for Bacterial Detection

Léguillier,

Heddi,

Vidic

2024

Biosensors

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The rapid and sensitive detection of pathogenic bacteria is becoming increasingly important for the timely prevention of contamination and the treatment of infections. Biosensors based on nucleic acid aptamers, integrated with optical, electrochemical, and mass-sensitive analytical techniques, have garnered intense interest because of their versatility, cost-efficiency, and ability to exhibit high affinity and specificity in binding bacterial biomarkers, toxins, and whole cells. This review highlights the development of aptamers, their structural characterization, and the chemical modifications enabling optimized recognition properties and enhanced stability in complex biological matrices. Furthermore, recent examples of aptasensors for the detection of bacterial cells, biomarkers, and toxins are discussed. Finally, we explore the barriers to and discuss perspectives on the application of aptamer-based bacterial detection.

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Section: Other Aptasensors For Bacterial Detectionmentioning

confidence: 99%

Recent Advances in Aptamer-Based Biosensors for Bacterial Detection

Léguillier,

Heddi,

Vidic

2024

Biosensors

View full text Add to dashboard Cite

show abstract

“…Many bacterial pathogens such as S. aureus, E. coli, C. botulinum, C. perfringens, C. difficile, B. cereus, C. jejuni, L. monocytogenes, Yersinia enterocolitica, and Salmonella spp. produce toxins [175][176][177][178][179][180][181][182][183]. Ingested bacteria toxins cause various effects, ranging from disrupting cell membranes and causing cell death to interfering with the host immune response.…”

Section: Bacterial Toxin Detectionmentioning

confidence: 99%

Aptamer-Based Biosensors for Bacterial Detection

Léguillier,

Heddi,

Vidic

2024

Preprint

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The rapid and sensitive detection of pathogenic bacteria is becoming increasingly important for the timely prevention of contamination and treatment of infections. Biosensors based on nucleic acid aptamers integrat-ed with optical, electrochemical, and mass-sensitive analytical techniques have garnered intense interest for their versatility, cost-efficiency, and ability to exhibit high affinity and specificity in binding bacterial bi-omarkers, toxins, and whole cells. This review emphasizes the development of aptamers, their structural op-timization, and their use in bacterial sensing applications. Moreover, we explore barriers and develop per-spectives in applying aptamer-based bacterial detection.

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