Statins and beta blockers - The most frequently encountered potential prescribing omissions in rural Romanian elderly population

Buda, Valentina; Dalleur, Olivia; Prelipcean, Andreea; Buda, S; Andor, Minodora; Baibata, Dana Emilia; Dohou, AM; Petrescu, Lucian; Cristescu, Carmen

doi:10.1016/j.atherosclerosis.2020.10.745

Cited by 1 publication

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“…The prevalence of PIMs varied widely among studies. Our study is consistent with some previous reports (Zhang et al, 2017;Buda et al, 2020;Bai et al, 2022), but inconsistent with others (Tommelein et al, 2015;Sheikh-Taha and Dimassi, 2017;Fernández et al, 2021). A total of 53.5% patients had at least one PIM identified by the Beers criteria (2015) reported by Zhang X et al at Peking University First Hospital (Zhang et al, 2017).…”

Section: Discussionsupporting

confidence: 78%

“…In the study by Bai et al, a low incidence of 20.6% was also found using the STOPP criteria. In addition, 25.80% patients had at least one PIM in Romania according to the STOPP criteria, though the prevalence of PPOs according to the START criteria was higher (41.72%) (Buda et al, 2020). The prevalence of PIMs was as high as 75% in community-dwelling older persons from five different cultural and social contexts: Kingston (Ontario, Canada), Saint-Hyacinthe (Quebec, Canada), Tirana (Albany), Manizales (Colombia), and Natal (Brazil) (Fernández et al, 2021).…”

Section: Discussionmentioning

confidence: 94%

“…High prevalence rates of PIM use vary in different healthcare settings, from 20.6% to 87.4% (Tommelein et al, 2015;Sheikh-Taha and Dimassi, 2017;Zhang et al, 2017;Buda et al, 2020;Fernández et al, 2021;Bai et al, 2022). This study aimed to investigate the prevalence of polypharmacy, PIM use, and the factors associated with PIM use in elderly people aged ≥65 admitted to the Geriatric Department of Shandong Provincial Hospital affiliated to Shandong First Medical University in order to monitor and minimize PIM use.…”

Section: Introductionmentioning

confidence: 99%

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Evaluation of potentially inappropriate medications for the elderly according to beers, STOPP, START, and Chinese criteria

Zhu,

Zhang,

Zhao

et al. 2024

Front. Pharmacol.

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Objective: Polypharmacy prevalence is increasing worldwide, and it is becoming more popular among the elderly. This study aimed to compare the prevalence of potentially inappropriate medications (PIMs) using the Beers criteria (2019 edition), criteria for potentially inappropriate medications for older adults in China (Chinese criteria), Screening Tool of Older Persons’ Prescriptions (STOPP), and Screening Tool to Alert to Right Treatment (START) criteria and to identify risk factors associated with PIM use.Methods: This was a cross-sectional study with a sample of 276 inpatients aged ≥65 years old from January 2020 to June 2020. A cross-sectional study was conducted to analyze PIMs based on the Beers (2019 edition), Chinese, STOPP, and START criteria. PIMs use was analysed based on four different criteria and logistic regression analysis was used to investigate independent factors associated with PIM use.Results: The mean number of medications used by the elderly population was nine (range, 0–28). A total of 252 patients (accounting for 91.30%) took five or more medications and 120 patients (accounting for 43.48%) took 10 or more medications. The prevalence rates of PIMs were 66.30% (183/276), 55.07% (152/276), 26.45% (73/276), and 64.13% (177/276) determined by the Beers, Chinese, STOPP, and START criteria, respectively. The top PIMs screened using the Beers, Chinese, and STOPP criteria were proton pump inhibitors, clopidogrel, and benzodiazepines, respectively. Missed use of ACEI in patients with systolic heart failure and/or coronary artery disease was found to be the most common potential prescription omission (PPOs) analyzed using the START criteria. Logistic regression analysis showed that the strongest predictor of PIMs, as determined by all four criteria, was an increased number of medications (p < 0.001). Age was another risk factor for PIMs based on the STOPP criteria in our study (p < 0.05).Conclusion: Polypharmacy and PIMs were common in our study, and the risk of PIMs correlated with polypharmacy. Application of the Beers, Chinese, STOPP, and START criteria is a useful tool for detecting PIM use.

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