“…The aim was to set up an in-vitro model of the size measurement of microscopic 99m Tc-HDP uptake that can be used clinically in in-vivo 99m Tc-HDP bone scan. Thus, the objectives of this study were first to secure the reliable source of microscopic 99m Tc-HDP deposits for micrometric measurement using standard flood phantom and handy small dish phantom; second, to demonstrate individual deposits with high 99m Tc-HDP radioactivity by GCPS [1,2]; and third, to mathematically calculate their size by pixelized measurement [4,5]. Microscopic 99m Tc-HDP deposits were easily formed in both large standard and small house-made dish phantoms, readily processed by GCPS and precisely calculated.…”