2024
DOI: 10.1177/17407745241265628
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Statistical approaches for component-wise censored composite endpoints

Anne Eaton

Abstract: Composite endpoints defined as the time to the earliest of two or more events are often used as primary endpoints in clinical trials. Component-wise censoring arises when different components of the composite endpoint are censored differently. We focus on a composite of death and a non-fatal event where death time is right censored and the non-fatal event time is interval censored because the event can only be detected during study visits. Such data are most often analysed using methods for right censored data… Show more

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