Statistically controlled biogenesis of silver nano-size by Penicillium chrysogenum MF318506 for biomedical application

Aty, Abeer A. Abd El; Mohamed, Asem A.; Zohair, Moustafa M.; Soliman, A. M.

doi:10.1016/j.bcab.2020.101592

Cited by 18 publications

(9 citation statements)

References 47 publications

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“…speciosa fruits, have been reported. For example, P. chrysogenum (isolate 13 in our work) has shown the ability to synthesize penicillin and xanthocillin X, treatment of pulp mill waste, production of polyamine oxidase, phospho-gluconate dehydrogenase, and glucose oxidase (Frisvad & Samson, 2004), and biogenesis of silver nano-nanoparticles (Abd El Aty et al, 2020). The species P. purpurogenum (isolate 17 in our work) has been shown as a potentially effective tool in the food industry (Zavaleta & Eyzaguirre, 2016) and production of the natural pigments (Tsiailanis et al, 2018;Pandit et al, 2020;Parul et al, 2020).…”

Section: Discussionmentioning

confidence: 87%

Endophytic community of Chaenomeles speciosa fruits: Screening for biodiversity and antifungal activity

Lykholat

Дідур

Drehval

et al. 2022

Regul. Mech. Biosyst.

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Fruit crops of the genus Chaenomeles Lindl are considered today as a superfood due to accumulation of biologically active compounds with antioxidant ability and known health-promoting properties. Successful introduction of this non-traditional culture in the steppe zone of Ukraine characterised by an unfavourable climate suggests the functioning of effective protective mechanisms in plants, including those that can be provided by the influence of endophytic microorganisms. However, there is little information about the endophytic community of Chaenomeles plants. Herein, the current study was aimed to isolate the endophytic fungi from the Ch. speciosa fruits and evaluate their biological activities against the phytopathogens. The study was carried out based on the collection of the Botanical Garden of Oles Honchar Dnipro National University (Dnipro city, Ukraine). Three media, namely PDA, MPA, and Gause’s medium were used for isolation of endophytic fungi. Colonies of isolates for identification were grown on PDA, Czapek's agar, and Czapek’s yeast autolysate media. Six fungal endophytic isolates derived from both peel and pulp of Ch. speciosa fruits have been morphologically identified using macroscopic and microscopic techniques, and assigned to the genus Penicillium (sections Chrysogena, Penicillium, Viridicata), and genus Talaromyces (section Talaromyces). Species P. expansum, P. viridicatum, and P. hirsutum were identified among the peel isolates, while P. chrysogenum, P. cyclopium, and P. purpurogenum were among the pulp isolates. Antagonistic ability of the endophytic isolates against phytopathogenic fungi was evaluated using the dual culture method. The results showed moderate to high antifungal capacity of the endophytic isolates against the phytopathogenic strains of the Fusarium genus. The growth inhibition of F. culmorum mycelium due to the influence of endophytic isolates was 51.5–81.3%, and the inhibition of the growth of F. oxysporum colonies was in the range of 68.4–86.6% as compared with control. There were no significant differences in the antagonistic ability between endophytic isolates derived from the peel and pulp of the fruit. Taken together, our findings indicated the great potential of the endophytic fungi from Ch. speciosa fruits as a source for the development of biocontrol agents and discovery of new bioactive compounds.

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Section: Discussionmentioning

confidence: 87%

Endophytic community of Chaenomeles speciosa fruits: Screening for biodiversity and antifungal activity

Lykholat

Дідур

Drehval

et al. 2022

Regul. Mech. Biosyst.

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“…The results obtained by Muhsin and Hachim (2016) showed that Tirmania nivea silver-nanoparticles exhibited an inhibition activity of (14.5–28 mm inhibition zones diameter) against the tested pathogenic bacterial strains like E. coli and P. aeruginosa. The model accuracy was validated under the maximum conditions, showed the best IZDs of trials 2, 6 and 11 and the obtained data showed the efficiency of the applied model and indicated the dependence of particles activity on the reaction conditions which affected the particles size and shape ( Abd El Aty et al, 2020 ).…”

Section: Discussionmentioning

confidence: 90%

“…Therefore, the Response surface methodology (RSM) with 13 experiments was applied for controlling the nanoparticles morphology and size, and help rapid AgNPs biosynthesis. ( Abd El Aty et al, 2020 , Ibrahim et al, 2021 ). All prepared Truffle-AgNPs (1–13) have better antimicrobial activities than the first reaction conditions (1 mM AgNO 3 and pH 7).…”

Section: Discussionmentioning

confidence: 99%

“…Response surface methodology (RSM) was an effective technique for controlling the nanoparticles morphology and size, that affecting AgNPs biological activities. In addition, improving the experimental factors like the amount of AgNO 3 , reducing agent, temperature, and pH using central composite design (CCD) decreasing time for rapid AgNPs biosynthesis ( Abd El Aty et al, 2020 , Ibrahim et al, 2021 ).…”

Section: Introductionmentioning

confidence: 99%

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Statically controlled mycogenic-synthesis of novel biologically active silver-nanoparticles using Hafr Al-Batin desert truffles and its antimicrobial efficacy against pathogens

Alshammari

Aty²

2022

Saudi Journal of Biological Sciences

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“…We have also mentioned other P. chrysogenum strains regarding their capacity to produce a large variety of secondary metabolites and which were isolated from very diverse ecological niches ( Table 1 ). Extending the field a little further, we can mention some additional biotechnological uses that are currently under investigation, such as the capacity of the Giza desert isolate P. chrysogenum MF318506 to produce nanoparticles with antimicrobial activities [ 361 , 362 ], the high bioremediation capacity against polychlorinated biphenyls (up to 96.5% removal) of two P. chrysogenum strains isolated from contaminated soils in France [ 363 ], and the use of an alginate-immobilized tyrosinase isolated from strain P. chrysogenum AUMC 14100 to remove phenol [ 364 ]. Additional biotechnology uses have been found for a mini-intein of only 157 amino acids present in the splicing-factor protein PRP8 of strain P. chrysogenum Pch-1 [ 365 ].…”

Section: Epiloguementioning

confidence: 99%

Penicillium chrysogenum, a Vintage Model with a Cutting-Edge Profile in Biotechnology

et al. 2022

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The discovery of penicillin entailed a decisive breakthrough in medicine. No other medical advance has ever had the same impact in the clinical practise. The fungus Penicillium chrysogenum (reclassified as P. rubens) has been used for industrial production of penicillin ever since the forties of the past century; industrial biotechnology developed hand in hand with it, and currently P. chrysogenum is a thoroughly studied model for secondary metabolite production and regulation. In addition to its role as penicillin producer, recent synthetic biology advances have put P. chrysogenum on the path to become a cell factory for the production of metabolites with biotechnological interest. In this review, we tell the history of P. chrysogenum, from the discovery of penicillin and the first isolation of strains with high production capacity to the most recent research advances with the fungus. We will describe how classical strain improvement programs achieved the goal of increasing production and how the development of different molecular tools allowed further improvements. The discovery of the penicillin gene cluster, the origin of the penicillin genes, the regulation of penicillin production, and a compilation of other P. chrysogenum secondary metabolites will also be covered and updated in this work.

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Statistically controlled biogenesis of silver nano-size by Penicillium chrysogenum MF318506 for biomedical application

Cited by 18 publications

References 47 publications

Endophytic community of Chaenomeles speciosa fruits: Screening for biodiversity and antifungal activity

Endophytic community of Chaenomeles speciosa fruits: Screening for biodiversity and antifungal activity

Statically controlled mycogenic-synthesis of novel biologically active silver-nanoparticles using Hafr Al-Batin desert truffles and its antimicrobial efficacy against pathogens

Penicillium chrysogenum, a Vintage Model with a Cutting-Edge Profile in Biotechnology

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