Status of Laparoscopic Sleeve Gastrectomy in China: A National Survey

Lin, Shibo; Guan, Wei; Hans, Pankaj Kumar; Liang, Hui

doi:10.1007/s11695-017-2727-1

Cited by 7 publications

(2 citation statements)

References 23 publications

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“…The management of post-LSG leak is multimodal, and no accepted algorithm for the diagnosis and treatment of GL has been proposed yet. In China, 84.8% of surgeons consider Roux-en-Y bypass as a salvage procedure, 142 whereas some researchers regard LRYEJ as a suitable technique after the failure of the endoscopic management of post-sleeve gastrectomy fistula. 133,134,143 The determination of surgical methods depends mainly on patient disposition.…”

Section: Revisional Surgeries For Gastric Leakmentioning

confidence: 99%

Revisional Surgeries of Laparoscopic Sleeve Gastrectomy

Li¹,

Jiao²,

Zhang³

et al. 2021

DMSO

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Bariatric surgery has become increasingly common due to the worldwide obesity epidemic. A shift from open to laparoscopic surgery, specifically, laparoscopic sleeve gastrectomy (LSG), has occurred in the last two decades because of the low morbidity and mortality rates of LSG. Although LSG is a promising treatment option for patients with morbid obesity due to restrictive and endocrine mechanisms, it requires modifications for a subset of patients because of weight regain and tough complications, such as gastroesophageal reflux, strictures, gastric leak, and persistent metabolic syndrome., Revision surgeries have become more and more indispensable in bariatric surgery, accounting for 7.4% in 2016. Mainstream revisional bariatric surgeries after LSG include Roux-en-Y gastric bypass, repeated sleeve gastrectomy, biliopancreatic diversion, duodenal switch, duodenal-jejunal bypass, one-anastomosis gastric bypass, single anastomosis duodeno-ileal bypass (SAID) and transit bipartition. This review mainly describes the revisional surgeries of LSG, including the indication, choice of surgical method, and subsequent effect.

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Section: Revisional Surgeries For Gastric Leakmentioning

confidence: 99%

Revisional Surgeries of Laparoscopic Sleeve Gastrectomy

Li¹,

Jiao²,

Zhang³

et al. 2021

DMSO

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“…Females are the predominant gender to receive bariatric procedures, especially adjustable gastric banding operations [5]. In China, the number of bariatric operations has increased annually [6]. e standard set by the Chinese Society for Metabolic and Bariatric Surgery (CSMBS), which is adhered to by most Chinese bariatric surgeons, to determine patients who are qualified for weight loss surgery is as follows: (1) BMI ≥32.5 kg/m 2 with or without type 2 diabetes mellitus (T2DM); (2) 27.5 kg/m 2 <BMI <32.5 kg/m 2 with T2DM but failed conservative treatment and combined with at least two metabolic diseases or comorbidities; (3) duration of T2DM ≤15 years with fasting C-peptide ≥50% of the normal lower limit; (4) waist circumference: male ≥90 cm, female ≥85 cm; and (5) age within 16∼65 years [6].…”

Section: Introductionmentioning

confidence: 99%

Comparative Proteomic Analysis of Visceral Adipose Tissue in Morbidly Obese and Normal Weight Chinese Women

Chen

Sun

Wang

et al. 2019

International Journal of Endocrinology

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Objective. Visceral adipose tissue (VAT) plays a central role in the balance of energy metabolism. The objective of this study was to investigate the differentially expressed proteins in VAT between morbidly obese (BMI >35 kg/m2) and normal weight Chinese women. Method. Nine morbidly obese women and 8 normal weight women as controls were enrolled. Abdominal VAT was excised and analyzed by label-free one-dimensional liquid chromatography tandem mass spectrometry (1D-LC-MS/MS). Differentially expressed VAT proteins were further analyzed with Gene Ontology (GO) analysis and Ingenuity Pathway Analysis (IPA). Masson’s trichrome staining and CD68 immunohistochemical staining of VAT were conducted in all subjects. Result. A total of 124 differentially expressed proteins were found with a ≥2-fold difference. Forty-one proteins were upregulated, and 83 proteins were downregulated in obese individuals. These altered VAT proteins were involved in the attenuation of the liver X receptor/retinoid X receptor (LXR/RXR) signaling pathway and the activation of the acute-phase response process. Three proteins (ACSL1, HADH, and UCHL1) were validated by western blotting using the same set of VAT samples from 6 morbidly obese and 7 normal weight patients, and the results indicated that the magnitude and direction of the protein changes were in accordance with the proteomic analysis. Masson’s trichrome staining and CD68 immunohistochemical staining demonstrated that there was much more collagen fiber deposition and CD68-positive macrophages in the VAT of morbidly obese patients, suggesting extensive fiber deposition and macrophage infiltration. Conclusion. A number of differentially expressed proteins were identified in VAT between morbidly obese and normal weight Chinese females. These differential proteins could be potential candidates in addressing the role of VAT in the development of obesity.

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