Steady magnetic fields effect on lipid peroxidation kinetics

Abstract

The effect of steady magnetic fields (ranging from 0 to 280 mT) has been investigated on the kinetics of non-enzymatic lipid peroxidation occurring in a model system consisting of liposomes obtained from 1, 2-dioleoylphosphatidylcholine by oxygen consumption. The process was found to be accelerated by weak steady magnetic fields. A computer simulation method was employed to detect the reactions that govern the process kinetics, to elucidate magneto-sensitive stages (initiation and reduction of iron(III), as well as lipid peroxide radical recombination) and to determine their rate constants at various external magnetic fields. The kinetics of peroxidation of lipid cell membranes have been modeled mathematically at oxygen and 'free' iron concentrations close to those in the cells and also at increased free iron concentrations at different external magnetic field values.

Effects of Continuous and Intermittent Magnetic Fields on Oxidative Parameters In vivo

“…Studies showed that exposure to ELF-MF caused increased lipid peroxidation [13,14]. Fiorani et al [15] suggested that 50 Hz 0.5 mT magnetic field increased the damage in an oxidatively stressed erythrocyte system.…”

Does static magnetic field-exposure induced oxidative stress and apoptosis in rat kidney and muscle? Effect of vitamin E and selenium supplementations

“…Aristarkhov et al (1983) demonstrated an increase of lipid peroxidation level in liposomes (1,2-dioleophosphatidylcholine) exposed to SMF (8 mT). SMF, under in vitro chemical stimulation, can influence lipid peroxidation kinetics in liposomes and enhance the production of oxygen free radicals in human red blood cells (Lalo et al 1994;Chignell and Sik 1998). Previous studies by Amara et al (2006Amara et al ( , 2007Amara et al ( , 2009) showed an increase in MDA level in male rat testis, hippocampus, liver and kidney after exposure to SMF (128 mT, 1 h/day during 30 consecutive days).…”

The effect of 50 hz magnetic field of different shape on oxygen metabolism in blood platelets: in vitro studies

“…Increased lipid peroxidation was observed for steady MF of flux density of ca. 8 mT [18]. Artificial phospholipid membranes were used in this test.…”