2015
DOI: 10.3109/13880209.2014.1001407
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Stem bark and flower extracts ofVismia caulifloraare highly effective antioxidants to human blood cells by preventing oxidative burst in neutrophils and oxidative damage in erythrocytes

Abstract: (2015) Stem bark and flower extracts of Vismiacauliflora are highly effective antioxidants to human blood cells by preventing oxidative burst in neutrophils and oxidative damage in erythrocytes, Pharmaceutical Biology, 53:11, 1691-1698, DOI: 10.3109/13880209.2014 Previous research on V. cauliflora extracts suggests its potential to neutralize cellular oxidative damages related to the production of reactive oxygen and nitrogen species.Objective: To determine the activity of stem bark and flower extracts of V. … Show more

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Cited by 10 publications
(6 citation statements)
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“…Phenolic compounds are known to donate hydrogen to reduce oxidative damage by detoxifying free radicals [ 61 , 62 ]. These compounds are also reported to activate the endogenous system of antioxidants and repressed lipid peroxidation of erythrocytes in humans [ 63 , 64 ].…”
Section: Resultsmentioning
confidence: 99%
“…Phenolic compounds are known to donate hydrogen to reduce oxidative damage by detoxifying free radicals [ 61 , 62 ]. These compounds are also reported to activate the endogenous system of antioxidants and repressed lipid peroxidation of erythrocytes in humans [ 63 , 64 ].…”
Section: Resultsmentioning
confidence: 99%
“…Phenolic compounds are hydrogen donors capable of directly scavenging free radicals and reducing oxidative damage [42,43], which makes them potent antioxidants. In other medicinal plant extracts, these compounds also activated endogenous antioxidant systems and inhibited the lipid peroxidation of human erythrocytes [2, 44]. Among the phenolic compounds, flavonoids are the most prominent because of their potent antioxidant activity [45].…”
Section: Discussionmentioning
confidence: 99%
“…Superoxide radical formation is the first step for the generation of oxygen species, being considered the starting point of oxidative stress [53,54]. According to Table 4, the optimal extract presented an IC 50 = 14.1 µg/mL for the scavenging of this species, being lower than the result obtained for catechin (IC 50 = 49.0 µg/mL).…”
Section: Ros and Rns Scavenging Assaysmentioning
confidence: 96%