Stem cells: From embryology to cellular therapy? An appraisal of the present state of art

Eridani, S; Sgaramella, Vittorio; Cova, Lidia

doi:10.1007/s10616-004-2067-6

Cited by 12 publications

(11 citation statements)

References 115 publications

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“…The first author Hwang, Woo Suk and his corresponding institution Seoul National University College of Veterinary Medicine are assigned to A t and I t , respectively. From all articles that cited the retracted paper, the first one published (Eridani, Sgaramella, & Cova, 2004) is assigned to P t citing . From all articles that share references with the retracted paper, we select the one with the largest Jaccard coefficient between both reference sets (Tabar & Studer, 2002) and assign it to P t coref .…”

Section: Selecting Treatment Entities and Specifying Retraction Yearmentioning

confidence: 99%

A Multidimensional Investigation of the Effects of Publication Retraction on Scholarly Impact

Shuai

Rollins

Moulinier

et al. 2017

Asso for Info Science & Tech

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During the past few decades, the rate of publication retractions has increased dramatically in academia. In this study, we investigate retractions from a quantitative perspective, aiming to answer two fundamental questions. One, how do retractions influence the scholarly impact of retracted papers, authors, and institutions? Two, does this influence propagate to the wider academic community through scholarly associations? Specifically, we analyzed a set of retracted articles indexed in Thomson Reuters Web of Science (WoS), and ran multiple experiments to compare changes in scholarly impact against a control set of nonretracted articles, authors, and institutions. We further applied the Granger Causality test to investigate whether different scientific topics are dynamically affected by retracted papers occurring within those topics. Our results show two key findings: first, the scholarly impact of retracted papers and authors significantly decreases after retraction, and the most severe impact decrease correlates with retractions based on proven, purposeful scientific misconduct; second, this retraction penalty does not seem to spread through the broader scholarly social graph, but instead has a limited and localized effect. Our findings may provide useful insights for scholars or science committees to evaluate the scholarly value of papers, authors, or institutions related to retractions.

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Section: Selecting Treatment Entities and Specifying Retraction Yearmentioning

confidence: 99%

A Multidimensional Investigation of the Effects of Publication Retraction on Scholarly Impact

Shuai

Rollins

Moulinier

et al. 2017

Asso for Info Science & Tech

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“…The use of cell culture is increasing exponentially, and new in vitro alternatives are constantly being developed and applied. The propagation and expansion of human cells in tissue engineering (Minuth et al, 1998;Risbud and Sittinger, 2002;Stock and Vacanti, 2001), and in (adult) stem cell technology and cell based therapy has gained increasing importance (Bianco and Robey, 2001;Czyz et al, 2003;Eridani et al, 2004;tsonis, 2002;Zandstra and Nagy, 2001). In addition, during the past decade, invertebrate cell and tissue culture has become a prominent tool in biotechnological applications, since cultured insect cells are widely used as eukaryotic in vitro expression systems using baculovirus expression vectors (Fraser, 1992;Jarvis, 1991;Condreay, 1999, 2002;Kost et al, 2005;McCarroll and King, 1997).…”

Section: Introductionmentioning

confidence: 99%

Serum-free cell culture: the serum-free media interactive online database

Brunner

Frank²,

Appl³

et al. 2010

ALTEX

324

232

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Prefacethe supplementation of basal culture media with animal serum of different origins is essential for cell growth, metabolism, and to stimulate proliferation ("mitogenic effect"). the sera used most widely are bovine sera of adult or newborn animals, or of fetal origin. Fetal bovine serum (FBS) is a cocktail of most of the factors required for cell attachment, growth and proliferation and is thus used as an almost universal growth supplement effective for most types of human and animal (including insect) cells. However, the use of animal serum in cell culture also bears a number of disadvantages. these disadvantages can be seen either from -a theoretical, cell biological point of view, since serum in general is an ill-defined mixture of components in culture media, -from ethical perspectives in terms of animal protection arguments regarding the harvest and collection of FBS from bovine fetuses and -in terms of recent concerns about the global supply versus demand of FBS. As a consequence, a number of strategies were developed to reduce or replace the requirement for FBS in cell culture media. -Furthermore, recent advances in biomedicine, tissue engineering and (adult mesenchymal) stem cell-based therapy demand innovative serum-alternatives of human origin for autologous cell expansion and reimplantation. Also, for the biotechno-

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“…Both self-renewal and differentiation are required abilities in any cell of the hematopoietic lineage [39]. However, the expansion of these cells in vitro has been challenging for the scientific community, as regulation of these cells depends on several mechanisms of intercellular communication resulting from the secretion of local-and systemic-acting factors [40]. HSCs, which can also be obtained and expanded from umbilical cord blood, should respond to and integrate events in their microenvironment to ensure sustained production of all hematopoietic lineages [41].…”

Section: Stem Cell Culture Methodsmentioning

confidence: 99%

Traditional and Advanced Cell Cultures in Hematopoietic Stem Cell Studies

Ribeiro-Filho

Levy

Ruiz

et al. 2019

Cells

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Hematopoiesis is the main function of bone marrow. Human hematopoietic stem and progenitor cells reside in the bone marrow microenvironment, making it a hotspot for the development of hematopoietic diseases. Numerous alterations that correspond to disease progression have been identified in the bone marrow stem cell niche. Complex interactions between the bone marrow microenvironment and hematopoietic stem cells determine the balance between the proliferation, differentiation and homeostasis of the stem cell compartment. Changes in this tightly regulated network can provoke malignant transformation. However, our understanding of human hematopoiesis and the associated niche biology remains limited due to accessibility to human material and the limits of in vitro culture models. Traditional culture systems for human hematopoietic studies lack microenvironment niches, spatial marrow gradients, and dense cellularity, rendering them incapable of effectively translating marrow physiology ex vivo. This review will discuss the importance of 2D and 3D culture as a physiologically relevant system for understanding normal and abnormal hematopoiesis.

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Stem cells: From embryology to cellular therapy? An appraisal of the present state of art

Abstract: A series of publications has dealt in the last years with topics as the isolation, properties and applications of animal stem cells

Cited by 12 publications

References 115 publications

A Multidimensional Investigation of the Effects of Publication Retraction on Scholarly Impact

A Multidimensional Investigation of the Effects of Publication Retraction on Scholarly Impact

Serum-free cell culture: the serum-free media interactive online database

Traditional and Advanced Cell Cultures in Hematopoietic Stem Cell Studies

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