Stereospecific ligands and their complexes. XXII. Synthesis and antitumor activity of palladium(II) complexes with some esters of (S,S)-ethylenediamine-N,N′-di-(2,2′-di(4-hydroxy-benzyl))-acetic acid
“…Correspondingly, previous research has shown that palladium( ii ) complexes with certain esters of ( S , S )-ethylenediamine- N , N ′-di-(2,2′-di(4-hydroxy-benzyl))-acetic acid and their ligand precursors also exhibited dose-dependent cytotoxic effects towards various human cancer cell lines, including MDA-MB-231 (breast cancer), A549 (lung cancer), and CLL lymphocytes (chronic lymphocytic leukemia cells). 25…”
The four new ligands, dialkyl esters type of ligands (R2-S,S-pddtyr·2HCl) and corresponding palladium(ii) complexes have been synthesized, characterized, and their biological activities were investigated.
“…Correspondingly, previous research has shown that palladium( ii ) complexes with certain esters of ( S , S )-ethylenediamine- N , N ′-di-(2,2′-di(4-hydroxy-benzyl))-acetic acid and their ligand precursors also exhibited dose-dependent cytotoxic effects towards various human cancer cell lines, including MDA-MB-231 (breast cancer), A549 (lung cancer), and CLL lymphocytes (chronic lymphocytic leukemia cells). 25…”
The four new ligands, dialkyl esters type of ligands (R2-S,S-pddtyr·2HCl) and corresponding palladium(ii) complexes have been synthesized, characterized, and their biological activities were investigated.
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