Stereospecificity and Self-Selectivity in the Generation of a Chiral Molecular Tetrahedron by Metal-Assisted Self-Assembly

Abstract

The chiral bidentate ligand (S,S)-1 reacts stereospecifically with Ga to generate a [Ga (L) ] molecular tetrahedron although similar ligands generate [Ga (L) ] complexes. The assembly of this complex is self-selective as a racemic mixture of the ligand sorts by chirality to generate an enantiomeric pair of homochiral complexes.

Structural design principles for self-assembled coordination polygons and polyhedra

“…Inspection of the output reveals that this run successfully identifies previously reported bis-catecholamide ligands that direct the formation of D 3 symmetric V 2 E 3 assemblies, including those crystallographically characterized, H1 and H3 (Fig. 16), as well as H14-H18 inferred by spectroscopic means 75,129,130 (Fig. 33).…”

Making a Right or Left Choice: Chiral Self-Sorting as a Tool for the Formation of Discrete Complex Structures

“…Hexacoordinate octahedral geometry is also observed for Ga 3+ ions forming Ga 4 (93a) 6 12− clusters (Figure 41a,b). 157 For S-93a, only one set of signals is observed in the NMR spectrum in D 2 O, and for rac-93a the spectrum is identical. X-ray structure indicates that homochiral T-symmetric clusters (Λ,Λ,Λ,Λ)-[Ga 4 (S-93a) 6 ] 12− with all hydrophobic methyl groups buried inside the cavity are formed.…”

Complexity with simplicity: a steric continuum of chelating diamines with copper(i) and dioxygen

“…42 The enantiomeric purity of cyd L used in these studies is also advantageous in the self-assembly process of polynuclear Cu-O 2 complexes, as the probability of forming diastereomeric products is significantly reduced. 26,33,[43][44][45] In the three series of ligands, the greatest difference is the lesser metal bite-angle of the five-atom chelating ligands, ed L and cyd L, as compared to the six-atom chelate ligands, pd L.…”