2012
DOI: 10.4149/neo_2012_015
|View full text |Cite
|
Sign up to set email alerts
|

Stereotactic radiotherapy (SBRT) as a sole or salvage therapy in non-small cell lung cancer patients

Abstract: The aim of this study is to present evaluation of treatment toxicity and the rate of local control in non-small cell lung cancer patients (NSCLC) treated with stereotactic body radiotherapy (SBRT). The analysis was performed on heterogenous group of 61 NSCLC patients, treated with SBRT between 2005 and 2008. It included 26 patients in clinical stage I, 5 in stage II, 22 in III and 8 in stage IV. In 30 patients SBRT was the only treatment, in 20 patients SBRT was a salvage therapy and in 11 patients SBRT was us… Show more

Help me understand this report

Search citation statements

Order By: Relevance

Paper Sections

Select...
2
1
1
1

Citation Types

0
5
0

Year Published

2012
2012
2023
2023

Publication Types

Select...
7

Relationship

0
7

Authors

Journals

citations
Cited by 7 publications
(5 citation statements)
references
References 21 publications
0
5
0
Order By: Relevance
“…The median (80%) isodose line (70–94%) of all the patients covered the planning target volume (PTV), which encompassed 3–8 mm outside the gross tumor volume (Table ). All targets received 2000 cGy in each of three fractions …”
Section: Methodsmentioning
confidence: 99%
“…The median (80%) isodose line (70–94%) of all the patients covered the planning target volume (PTV), which encompassed 3–8 mm outside the gross tumor volume (Table ). All targets received 2000 cGy in each of three fractions …”
Section: Methodsmentioning
confidence: 99%
“…Conceptually, surgical disruption of tissue and tissue vasculature may affect tumor control or toxicity risks, though is difficult to study. In a Polish study of 61 patients treated with SBRT alone, SBRT for boost or SBRT for salvage after resection (39), those who underwent salvage therapy (n=20) experienced worse LC compared to those treated with SBRT alone or as a boost (27% vs. 63% and 54% respectively, P=0.02). The authors postulated that in the salvage setting, LC was compromised because more conservative dosing was used out of consideration of normal tissue tolerance.…”
Section: Comparative Outcome Between Salvage Sbrt After Prior Resectimentioning
confidence: 99%
“…Stereotactic radiosurgery (SRS) and SBRT are techniques for delivering very high doses in a single or in a few fractions (hypofractionation) in order to shorten treatment duration and escalate the biological equivalent dose (Dworzecki et al, 2012). SRS and SBRT require a high degree of precision requiring tumor motion compensation and improved targeting of metabolically active tumor.…”
Section: Introductionmentioning
confidence: 99%