2014
DOI: 10.1016/j.ijpharm.2014.10.061
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Sterically stabilized polymeric nanoparticles with a combinatorial approach for multi drug resistant cancer: In vitro and in vivo investigations

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Cited by 35 publications
(15 citation statements)
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“…39,49 This approach allows researchers to measure the complex's log P empirically and fully characterize it using techniques such as differential scanning calorimetry (DSC), X-ray diffraction (XRD), NMR, FTIR, etc. 79 Isolated complexes are oen loaded into an oil phase or organic solvent (e.g. DCM 80,81 or acetone 82 ) and treated as a lipophilic molecule.…”
Section: Thymopentinmentioning
confidence: 99%
“…39,49 This approach allows researchers to measure the complex's log P empirically and fully characterize it using techniques such as differential scanning calorimetry (DSC), X-ray diffraction (XRD), NMR, FTIR, etc. 79 Isolated complexes are oen loaded into an oil phase or organic solvent (e.g. DCM 80,81 or acetone 82 ) and treated as a lipophilic molecule.…”
Section: Thymopentinmentioning
confidence: 99%
“…Currently, advances in nanotechnology have made it possible to improve the solubility, bioavailability, and absorbency of medicinal herbs as well as couple these advances with using a reduced dose and a sustained steady-state of therapeutic level of drugs over an extended period compared with the traditional methods [8][9][10][11] . Among the numerous nano-suspensions, the colloidal delivery system of polymeric nanoparticles has attracted much attention as a result of its unique properties, such as high biocompatibility, non-toxic nature, long-term stability, good physiological features, and acceptable control release [12,13] . The polymeric nanoparticles with smaller particle sizes (approximately 200 nm) could also increase drug accumulation in tumor cells via enhanced permeability and retention (EPR) effects [14][15][16] .…”
Section: Introductionmentioning
confidence: 99%
“…HA coated SLM loaded PLGA nanoparticles (SLM-HA-NPs) were prepared by emulsion solvent diffusion technique, according to an earlier reported method with some modifications [32,33]. Briefly, 22.5 mg polymer was dissolved in 2.25 ml ethyl acetate and to this 2.5 mg of SLM was added in 0.25 ml of ethanol.…”
Section: Preparation Of Ha Coated Slm-npsmentioning
confidence: 99%