STEROIDAL [3,2-c]PYRAZOLES

Synthesis and Antimicrobial Activity of Some New Benzimidazole Derivatives

“…Also, some heterocyclic moieties such as triazole nucleus are known to possess antibacterial [10] and fungicidal [11] properties. Furthermore, Schiff's bases possess anticancer [12,13] activity in animal screening, and pyrazoles, pyrazolones and alkylpyrazoles have shown wide ranging pharmacological applications [14]. We report here the synthesis of some derivatives of the title structure type containing the above mentioned moieties for evaluation of their antimicrobial activity.…”

Total synthesis of steroids and heterosteroids from BISTRO

“…Among the various known analogues of steroids, heterosteroids have received much attention in view of their different and interesting biological activities demonstrated [72][73][74][75][76][77][78][79][80][81][82][83]. The replacement of one or more carbon atoms of a steroid molecule by a heteroatom affects chemical properties of the steroid and often results in useful alterations to its biological activity.…”

Synthesis and structural characterization of products condensation 4-carboxy-1-(4-styrylcarbonylphenyl)-2-pyrrolidinones with hydrazines

“…Some pyrazoline derivatives were used as the bacteriostatic, fungicidal, and anticancer agents. [5] We continued our interest in the chemistry of N-substituted amino acids and the products of their cyclization, in this case -1,3-disubstituted 2-pyrrolidinones. The structure of newly synthesized compounds was mainly characterized by NMR spectroscopy.…”