2010
DOI: 10.1016/j.bbrc.2010.10.049
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Stimulation of Na+/K+ ATPase activity and Na+ coupled glucose transport by β-catenin

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Cited by 21 publications
(13 citation statements)
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“…2, G-I). In this regard, Na ϩ -K ϩ -ATPase not only sends ␤-catenin to the nucleus but is activated by the overexpression of ␤-catenin in oocytes (98). As previously shown by Nelson and coworkers (83), Liu et al (71) have recently found evidence that Na ϩ -K ϩ -ATPase and E-cadherin are closely associated, indicating that the pump might be a component of the adherens junction.…”
Section: Hormone Ouabain Modulates Cell Contactsmentioning
confidence: 75%
“…2, G-I). In this regard, Na ϩ -K ϩ -ATPase not only sends ␤-catenin to the nucleus but is activated by the overexpression of ␤-catenin in oocytes (98). As previously shown by Nelson and coworkers (83), Liu et al (71) have recently found evidence that Na ϩ -K ϩ -ATPase and E-cadherin are closely associated, indicating that the pump might be a component of the adherens junction.…”
Section: Hormone Ouabain Modulates Cell Contactsmentioning
confidence: 75%
“…Because β‐catenin plays a key role in regulating gene expression, and in HSA‐β‐cat −/− mice the levels of α2NKA mRNA were decreased, β‐catenin is likely to regulate α2NKA expression via its co‐transcriptional function. This conclusion was reached by others who showed that the expression of β‐catenin enhances the endogenous Na,K‐ATPase current (Sopjani et al ., ). However, how muscle β‐catenin regulates α2NKA remains an open question.…”
Section: Discussionmentioning
confidence: 97%
“…According to in vitro studies, β-catenin enhances the activity of both SGLT1 and Na + /K + ATPase [56]. The stimulating effect of β-catenin on both Na + /K + ATPase and SGLT1 activity was observed even in the presence of actinomycin D, an inhibitor of transcription [56].…”
Section: Discussionmentioning
confidence: 96%