Stir bar sorptive extraction and comprehensive two-dimensional gas chromatography coupled to high-resolution time-of-flight mass spectrometry for ultra-trace analysis of organochlorine pesticides in river water

Qualitative and quantitative approaches in comprehensive two-dimensional gas chromatography

“…This analyte may be a contributor to neurodegenerative diseases, which demonstrates how GC × GC can be used for detection of disease markers. Ochiai et al coupled stir bar sorption extraction and high-resolution time-of-flight (TOF) MS to GC × GC for ultra-trace level (pg/L-ng/L range) analysis of organochlorine pesticides in river water [37]. The trace analytes were successfully separated and quantitated using narrow mass windows.…”

“…There are many applications which require this knowledge including environmental [37,41,82], forensics [42] and food and flavors [83][84][85][86]. GC × GC is an ideal technique for non-targeted analysis because it has the capability of separating many of the analytes in complex matrices due to its structured chromatograms and high peak capacity.…”

Theory and Practice of UHPLC and UHPLC–MS

“…GC Â GC has been rarely combined with HR-TOF MS; for instance, Ochiai et al (2011) used GC Â GCeHR-TOF MS to analyze (pretargeted) organochlorine pesticides and untargeted solutes in river water. Sample preparation was carried out through stir-bar sorptive extraction, an approach that contributed toward excellent limits of detection (in the 10e44 pg/L range).…”

“…It is evident that the identification of all the samples is rather long and tedious, and cannot be used for more complex samples and for large-scale studies. Peres et al (2013) reduced the information obtained by SPME-GC Â GCeTOF MS analyses of two Portugal varieties by performing a GCeolfactometry screening of the same samples. Fifteen odor active compounds were identified, based on their concentrations and odor thresholds, and information relative only to these analytes were extrapolated from the 2D analyses performed.…”

Development of a Screening Method for the Determination of PCBs in Water Using QuEChERS Extraction and Gas Chromatography-Triple Quadrupole Mass Spectrometry

“…15 The analysis of PCBs in environmental samples usually involves extraction of the analytes from the matrix, subsequent clean up of the extracts, and final chromatographic analysis. Soxhlet extraction (SE), 16 accelerated solvent extraction (ASE), 17 stir bar sorptive extraction (SBSE), 18 solid phase extraction (SPE) 19 and matrix solid phase dispersion (MSPD) 20 have been applied as extraction techniques in trace analysis. Though these established extraction and clean-up methods are effective, they are either time consuming or use hazardous chemicals or require expensive apparatus and consumables.…”