2014
DOI: 10.1002/cite.201400087
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Stirring and Stirred‐Tank Reactors

Abstract: Stirred-tank reactors are used throughout the process industry. They are not only applied in the chemical industry, but also in newer industrial sectors, such as biologics, pharmaceuticals, nanotechnology, and regenerative medicine. Certain features have not changed for many years, but the understanding of the physical processes occurring within has greatly increased. Since knowledge of the interaction between the physics of mixing, single-or multiphase, and the underlying science is critical, the physical pro… Show more

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Cited by 53 publications
(33 citation statements)
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“…This means that there is minor formation of internal structures when the liquid is at rest, which is why the process may be suitable for intermittent mixing. In addition, the risk of cavern-formation around the impeller and the presence of stagnant zones is low at low yield stress conditions [38].…”
Section: Viscositymentioning
confidence: 99%
“…This means that there is minor formation of internal structures when the liquid is at rest, which is why the process may be suitable for intermittent mixing. In addition, the risk of cavern-formation around the impeller and the presence of stagnant zones is low at low yield stress conditions [38].…”
Section: Viscositymentioning
confidence: 99%
“…The stirred tank reactor (STR) has been the dominant vessel of choice in the biotechnology industry since its inception (Nienow, ). It offers good liquid mixing as well as a decent gas‐to‐liquid mixing in systems where the volumetric gas input is relatively modest (Nienow and Wisdom, ).…”
Section: Introductionmentioning
confidence: 99%
“…The stirred tank reactor is the most frequently used in process industries [66] to bring about an excellent solid-liquid, gas-liquid or gas-solid-liquid contact. The adequate degree of suspension of solid particles mean homogenization of slurry so formed or a near homogenization such that the suspension ensures uniform process conditions leading to predictable results.…”
Section: Chemical-industrial Reactor Designmentioning
confidence: 99%